5WKZ

VH1-69 germline antibody predicted from CR6261

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (H)	Immunoglobulin heavy variable 1-69D,IgG H chain	polymer	250	26669.9	1	UniProt (A0A0B4J2H0) UniProt (S6BAM6) Pfam (PF07686)	Homo sapiens (Human)
2	B (L)	Lambda-chain (AA -20 to 215)	polymer	217	22835.3	1	UniProt (A2NUT2)	Homo sapiens (Human)
3	C (H)	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)
4	D, E (H, L)	water	water		18.0	343	Chemie (HOH)

Sequence modifications

H: 1 - 98 (UniProt: A0A0B4J2H0)

PDB	External Database	Details
His 99	-	linker
Met 100	-	linker
Gly 101	-	linker
Tyr 102	-	linker
Gln 103	-	linker
Leu 104	-	linker
Arg 105	-	linker
Glu 106	-	linker
Thr 107	-	linker
Met 108	-	linker
Asp 109	-	linker
Val 110	-	linker
Trp 111	-	linker
Gly 112	-	linker
Lys 113	-	linker

H: 114 - 224 (UniProt: S6BAM6)

PDB	External Database	Details
Gly 225	-	expression tag
Ser 226	-	expression tag
Gly 227	-	expression tag
Gly 228	-	expression tag
Gly 229	-	expression tag
Leu 230	-	expression tag
Asn 231	-	expression tag
Asp 232	-	expression tag
Ile 233	-	expression tag
Phe 234	-	expression tag
Glu 235	-	expression tag
Ala 236	-	expression tag
Gln 237	-	expression tag
Lys 238	-	expression tag
Ile 239	-	expression tag
Glu 240	-	expression tag
Trp 241	-	expression tag
His 242	-	expression tag
Glu 243	-	expression tag
Cys 244	-	expression tag
His 245	-	expression tag
His 246	-	expression tag
His 247	-	expression tag
His 248	-	expression tag
His 249	-	expression tag
His 250	-	expression tag

L: -1 - 215 (UniProt: A2NUT2)

PDB	External Database	Details
Tyr 97	-	insertion
Val 98	Gly 118	conflict

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	49505.1
Non-Polymers*	Number of molecules	1
	Total formula weight	96.1
All*	Total formula weight	49601.2

*Water molecules are not included.