5WKE
Crystal Structure of Human CD1b in Complex with PS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | T-cell surface glycoprotein CD1b | polymer | 300 | 33530.7 | 1 | UniProt (P29016) Pfam (PF16497) Pfam (PF07654) | Homo sapiens (Human) | |
| 2 | B (B) | Beta-2-microglobulin | polymer | 99 | 11748.2 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C (C) | alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G11971MR) | |||
| 4 | D (D) | alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1203.1 | 1 | In PDB GlyTouCan (G11460AB) | |||
| 5 | E (A) | tetracosyl octadecanoate | non-polymer | 621.1 | 1 | Chemie (CUY) | |||
| 6 | F (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 7 | G, H, R (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 8 | I, J, K, L, M... (A, B) | CHLORIDE ION | non-polymer | 35.5 | 7 | Chemie (CL) | |||
| 9 | N (A) | (19S,22S,25R)-25-amino-22-hydroxy-16,22,26-trioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9Z)-octadec-9-enoate | non-polymer | 746.0 | 1 | Chemie (P50) | |||
| 10 | O, P, Q (B) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 11 | U, V (A, B) | water | water | 18.0 | 331 | Chemie (HOH) |
Sequence modifications
A: 2 - 278 (UniProt: P29016)
| PDB | External Database | Details |
|---|---|---|
| Gly 279 | - | expression tag |
| Ser 280 | - | expression tag |
| Gly 281 | - | expression tag |
| Leu 282 | - | expression tag |
| Asn 283 | - | expression tag |
| Asp 284 | - | expression tag |
| Ile 285 | - | expression tag |
| Phe 286 | - | expression tag |
| Glu 287 | - | expression tag |
| Ala 288 | - | expression tag |
| Gln 289 | - | expression tag |
| Lys 290 | - | expression tag |
| Ile 291 | - | expression tag |
| Glu 292 | - | expression tag |
| Trp 293 | - | expression tag |
| His 294 | - | expression tag |
| Glu 295 | - | expression tag |
| His 296 | - | expression tag |
| His 297 | - | expression tag |
| His 298 | - | expression tag |
| His 299 | - | expression tag |
| His 300 | - | expression tag |
| His 301 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 45278.9 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1773.6 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2091.7 | |
| All* | Total formula weight | 49144.2 |
