5WIW
Crystal structure of murine 4-1BB N128A mutant from HEK293T cells in P43 space group
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | Tumor necrosis factor receptor superfamily member 9 | polymer | 143 | 15600.8 | 2 | UniProt (P20334) Pfam (PF00020) | Mus musculus (Mouse) | 4-1BB ligand receptor,T-cell antigen 4-1BB |
2 | C (C) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 894.8 | 1 | In PDB GlyTouCan (G42466VF) | |||
3 | D (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
4 | E, G (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
5 | F, H, I (A, B) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
6 | J, K (A, B) | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A, B: 24 - 160 (UniProt: P20334)
PDB | External Database | Details |
---|---|---|
Leu 22 | - | expression tag |
Glu 23 | - | expression tag |
Ala 128 | Asn 128 | engineered mutation |
Leu 161 | - | expression tag |
Val 162 | - | expression tag |
Pro 163 | - | expression tag |
Arg 164 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 31201.7 | |
Branched | Number of molecules | 1 |
Total formula weight | 894.8 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 693.6 | |
All* | Total formula weight | 32790.1 |