5WGB
Crystal Structure of the Human mitochondrial Cysteine Desulfurase in complex with ISD11 and E. coli ACP1 protein at 2.75A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Cysteine desulfurase, mitochondrial | polymer | 426 | 47395.2 | 1 | UniProt (Q9Y697) Pfam (PF00266) In PDB | Homo sapiens (Human) | |
2 | B | LYR motif-containing protein 4 | polymer | 91 | 10763.5 | 1 | UniProt (Q9HD34) Pfam (PF05347) In PDB | Homo sapiens (Human) | |
3 | C | Acyl carrier protein | polymer | 77 | 8514.3 | 1 | UniProt (B7MJ81) Pfam (PF00550) In PDB | Escherichia coli O45:K1 (strain S88 / ExPEC) | ACP |
4 | A | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
5 | C | S-[2-({N-[(2R)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] dodecanethioate | non-polymer | 540.7 | 1 | Chemie (8Q1) |
Sequence modifications
A: 56 - 457 (UniProt: Q9Y697)
B: 1 - 91 (UniProt: Q9HD34)
PDB | External Database | Details |
---|---|---|
Met 32 | - | initiating methionine |
Gly 33 | - | expression tag |
Ser 34 | - | expression tag |
Ser 35 | - | expression tag |
His 36 | - | expression tag |
His 37 | - | expression tag |
His 38 | - | expression tag |
His 39 | - | expression tag |
His 40 | - | expression tag |
His 41 | - | expression tag |
Ser 42 | - | expression tag |
Ser 43 | - | expression tag |
Gly 44 | - | expression tag |
Leu 45 | - | expression tag |
Val 46 | - | expression tag |
Pro 47 | - | expression tag |
Arg 48 | - | expression tag |
Gly 49 | - | expression tag |
Ser 50 | - | expression tag |
His 51 | - | expression tag |
Met 52 | - | expression tag |
Leu 53 | - | expression tag |
Glu 54 | - | expression tag |
Met 55 | - | expression tag |
PDB | External Database | Details |
---|---|---|
Ala 11 | Ser 11 | conflict |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 66672.9 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 787.8 | |
All* | Total formula weight | 67460.7 |