5WG8
Structure of PP5C with LB-100; 7-oxabicyclo[2.2.1]heptane-2,3-dicarbonyl moiety modeled in the density
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein phosphatase 5 | polymer | 333 | 37887.0 | 1 | UniProt (P53041) Pfam (PF08321) Pfam (PF00149) | Homo sapiens (Human) | PP5,Protein phosphatase T,PPT |
| 2 | B, C (A) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) PubChem (27854) | |||
| 3 | D (A) | (1S,2R,3S,4R)-3-(4-methylpiperazine-1-carbonyl)-7-oxabicyclo[2.2.1]heptane-2-carboxylic acid | non-polymer | 268.3 | 1 | Chemie (LB1) PubChem (18558124) PubChem (18558126) PubChem (25007767) PubChem (44816506) PubChem (45101433) PubChem (132043224) PubChem (68257106) PubChem (99642420) PubChem (99642421) PubChem (3578572) PubChem (124578215) PubChem (124578216) PubChem (124583960) PubChem (8099538) PubChem (132053467) PubChem (11923097) PubChem (11923099) | |||
| 4 | E (A) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 5 | F (A) | (4R)-2-METHYLPENTANE-2,4-DIOL | non-polymer | 118.2 | 1 | Chemie (MRD) PubChem (7870) PubChem (5288834) PubChem (5288845) | |||
| 6 | G (A) | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
A: 169 - 499 (UniProt: P53041)
| PDB | External Database | Details |
|---|---|---|
| Gly 167 | - | expression tag |
| Ala 168 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37887.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 614.5 | |
| All* | Total formula weight | 38501.6 |
