5WEN

GluA2 bound to GSG1L in digitonin, state 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Glutamate receptor 2,Germ cell-specific gene 1-like protein	polymer	1057	117471.2	4	UniProt (P19491) UniProt (D3Z7H4) Pfam (PF01094) Pfam (PF10613) Pfam (PF00060) Pfam (PF07803)	Rattus norvegicus (Rat)	GluR-2,AMPA-selective glutamate receptor 2,GluR-B,GluR-K2,Glutamate receptor ionotropic,AMPA 2,GluA2,GSG1-like protein
2	E, F (A, C)	Digitonin	non-polymer		1229.3	2	Chemie (AJP)

Sequence modifications

A, B, C, D: 10 - 998 (UniProt: P19491)

PDB	External Database	Details
Glu 241	Asn 256	engineered mutation
Leu 382	Val 397	engineered mutation
-	Leu 399	deletion
-	Thr 400	deletion
-	Glu 401	deletion
-	Leu 402	deletion
-	Pro 403	deletion
-	Ser 404	deletion
Glu 384	Gly 405	engineered mutation
Asp 385	Asn 406	engineered mutation
Gln 392	Asn 413	engineered mutation
Gly 999	-	linker
Thr 1000	-	linker
Gly 1001	-	linker

A, B, C, D: 1002 - 1238 (UniProt: D3Z7H4)

PDB	External Database	Details
Leu 1151	Val 151	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	469884.8
Non-Polymers*	Number of molecules	2
	Total formula weight	2458.6
All*	Total formula weight	472343.5

*Water molecules are not included.