5WE6
70S ribosome-EF-Tu H84A complex with GTP and cognate tRNA
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 23S rRNA | polymer | 2903 | 941548.4 | 1 | GenBank (731469900) | Escherichia coli | |
| 2 | B (B) | 5S rRNA | polymer | 120 | 38813.1 | 1 | GenBank (1174070234) | Escherichia coli | |
| 3 | C (C) | 50S ribosomal protein L2 | polymer | 271 | 29663.2 | 1 | UniProt (P60422) Pfam (PF00181) Pfam (PF03947) | Escherichia coli | Large ribosomal subunit protein uL2 |
| 4 | D (D) | 50S ribosomal protein L3 | polymer | 208 | 22146.3 | 1 | UniProt (P60438) Pfam (PF00297) | Escherichia coli | Large ribosomal subunit protein uL3 |
| 5 | E (E) | 50S ribosomal protein L4 | polymer | 200 | 21990.4 | 1 | UniProt (P60723) Pfam (PF00573) | Escherichia coli | Large ribosomal subunit protein uL4 |
| 6 | F (F) | 50S ribosomal protein L5 | polymer | 177 | 20073.2 | 1 | UniProt (P62399) Pfam (PF00281) Pfam (PF00673) | Escherichia coli | Large ribosomal subunit protein uL5 |
| 7 | G (G) | 50S ribosomal protein L6 | polymer | 174 | 18543.2 | 1 | UniProt (P0AG55) Pfam (PF00347) | Escherichia coli | Large ribosomal subunit protein uL6 |
| 8 | H (H) | 50S ribosomal protein L9 | polymer | 149 | 15789.0 | 1 | UniProt (P0A7R1) Pfam (PF01281) Pfam (PF03948) | Escherichia coli | Large ribosomal subunit protein bL9 |
| 9 | I (I) | 50S ribosomal protein L11 | polymer | 141 | 14763.2 | 1 | UniProt (P0A7J7) Pfam (PF03946) Pfam (PF00298) | Escherichia coli | Large ribosomal subunit protein uL11 |
| 10 | J (J) | 50S ribosomal protein L13 | polymer | 141 | 15937.4 | 1 | UniProt (P0AA10) Pfam (PF00572) | Escherichia coli | Large ribosomal subunit protein uL13 |
| 11 | K (K) | 50S ribosomal protein L14 | polymer | 122 | 13451.9 | 1 | UniProt (A7ZSJ9) Pfam (PF00238) UniProt (by SIFTS) (P0ADY3) | Escherichia coli | |
| 12 | L (L) | 50S ribosomal protein L15 | polymer | 142 | 14748.2 | 1 | UniProt (P02413) Pfam (PF00828) | Escherichia coli | Large ribosomal subunit protein uL15 |
| 13 | M (M) | 50S ribosomal protein L16 | polymer | 136 | 15312.3 | 1 | UniProt (P0ADY7) Pfam (PF00252) | Escherichia coli | Large ribosomal subunit protein uL16 |
| 14 | N (N) | 50S ribosomal protein L17 | polymer | 119 | 13592.8 | 1 | UniProt (P0AG44) Pfam (PF01196) | Escherichia coli | Large ribosomal subunit protein bL17 |
| 15 | O (O) | 50S ribosomal protein L18 | polymer | 116 | 12663.5 | 1 | UniProt (P0C018) Pfam (PF00861) | Escherichia coli | Large ribosomal subunit protein uL18 |
| 16 | P (P) | 50S ribosomal protein L19 | polymer | 114 | 13028.1 | 1 | UniProt (P0A7K6) Pfam (PF01245) | Escherichia coli | Large ribosomal subunit protein bL19 |
| 17 | Q (Q) | 50S ribosomal protein L20 | polymer | 115 | 13212.6 | 1 | UniProt (P0A7L3) Pfam (PF00453) | Escherichia coli | Large ribosomal subunit protein bL20 |
| 18 | R (R) | 50S ribosomal protein L21 | polymer | 102 | 11515.3 | 1 | UniProt (P0AG48) Pfam (PF00829) | Escherichia coli | Large ribosomal subunit protein bL21 |
| 19 | S (S) | 50S ribosomal protein L22 | polymer | 109 | 12096.2 | 1 | UniProt (P61175) Pfam (PF00237) | Escherichia coli | Large ribosomal subunit protein uL22 |
| 20 | T (T) | 50S ribosomal protein L23 | polymer | 92 | 10415.3 | 1 | UniProt (P0ADZ0) Pfam (PF00276) | Escherichia coli | Large ribosomal subunit protein uL23 |
| 21 | U (U) | 50S ribosomal protein L24 | polymer | 102 | 11078.9 | 1 | UniProt (P60624) Pfam (PF00467) Pfam (PF17136) | Escherichia coli | Large ribosomal subunit protein uL24 |
| 22 | V (V) | 50S ribosomal protein L25 | polymer | 92 | 10511.2 | 1 | UniProt (P68919) Pfam (PF01386) | Escherichia coli | Large ribosomal subunit protein bL25 |
| 23 | W (W) | 50S ribosomal protein L27 | polymer | 75 | 8146.4 | 1 | UniProt (P0A7L8) Pfam (PF01016) | Escherichia coli | Large ribosomal subunit protein bL27 |
| 24 | X (X) | 50S ribosomal protein L28 | polymer | 77 | 8896.4 | 1 | UniProt (P0A7M2) Pfam (PF00830) | Escherichia coli | Large ribosomal subunit protein bL28 |
| 25 | Y (Y) | 50S ribosomal protein L29 | polymer | 60 | 7087.3 | 1 | UniProt (P0A7M6) Pfam (PF00831) | Escherichia coli | Large ribosomal subunit protein uL29 |
| 26 | Z (Z) | 50S ribosomal protein L30 | polymer | 56 | 6223.4 | 1 | UniProt (P0AG51) Pfam (PF00327) | Escherichia coli | Large ribosomal subunit protein uL30 |
| 27 | AA (0) | 50S ribosomal protein L32 | polymer | 55 | 6203.1 | 1 | UniProt (P0A7N4) Pfam (PF01783) | Escherichia coli | Large ribosomal subunit protein bL32 |
| 28 | BA (1) | 50S ribosomal protein L33 | polymer | 51 | 5928.0 | 1 | UniProt (P0A7N9) Pfam (PF00471) | Escherichia coli | Large ribosomal subunit protein bL33 |
| 29 | CA (2) | 50S ribosomal protein L34 | polymer | 45 | 5268.3 | 1 | UniProt (P0A7P5) Pfam (PF00468) | Escherichia coli | Large ribosomal subunit protein bL34 |
| 30 | DA (3) | 50S ribosomal protein L35 | polymer | 64 | 7181.8 | 1 | UniProt (P0A7Q1) Pfam (PF01632) | Escherichia coli | Large ribosomal subunit protein bL35,Ribosomal protein A |
| 31 | EA (4) | 50S ribosomal protein L36 | polymer | 38 | 4377.4 | 1 | UniProt (P0A7Q6) Pfam (PF00444) | Escherichia coli | Large ribosomal subunit protein bL36-A,Ribosomal protein B |
| 32 | FA (5) | 50S ribosomal protein L10 | polymer | 131 | 14112.3 | 1 | UniProt (P0A7J3) Pfam (PF00466) | Escherichia coli | 50S ribosomal protein L8,Large ribosomal subunit protein uL10 |
| 33 | GA (6) | 50S ribosomal protein L31 | polymer | 66 | 7516.7 | 1 | UniProt (P0A7M9) Pfam (PF01197) | Escherichia coli | Large ribosomal subunit protein bL31-A |
| 34 | HA (a) | 16S rRNA | polymer | 1539 | 498909.8 | 1 | GenBank (1114169151) | Escherichia coli | |
| 35 | IA (b) | 30S ribosomal protein S2 | polymer | 218 | 24253.9 | 1 | UniProt (P0A7V0) Pfam (PF00318) | Escherichia coli | Small ribosomal subunit protein uS2 |
| 36 | JA (c) | 30S ribosomal protein S3 | polymer | 206 | 23078.8 | 1 | UniProt (P0A7V3) Pfam (PF07650) Pfam (PF00189) | Escherichia coli | Small ribosomal subunit protein uS3 |
| 37 | KA (d) | 30S ribosomal protein S4 | polymer | 205 | 23383.0 | 1 | UniProt (P0A7V8) Pfam (PF00163) Pfam (PF01479) | Escherichia coli | Small ribosomal subunit protein uS4 |
| 38 | LA (e) | 30S ribosomal protein S5 | polymer | 157 | 16532.1 | 1 | UniProt (P0A7W1) Pfam (PF00333) Pfam (PF03719) | Escherichia coli | Small ribosomal subunit protein uS5 |
| 39 | MA (f) | 30S ribosomal protein S6 | polymer | 100 | 11669.4 | 1 | UniProt (P02358) Pfam (PF01250) | Escherichia coli | Small ribosomal subunit protein bS6 |
| 40 | NA (g) | 30S ribosomal protein S7 | polymer | 151 | 16861.5 | 1 | UniProt (P02359) Pfam (PF00177) | Escherichia coli | Small ribosomal subunit protein uS7 |
| 41 | OA (h) | 30S ribosomal protein S8 | polymer | 129 | 14015.4 | 1 | UniProt (P0A7W7) Pfam (PF00410) | Escherichia coli | Small ribosomal subunit protein uS8 |
| 42 | PA (i) | 30S ribosomal protein S9 | polymer | 127 | 14554.9 | 1 | UniProt (P0A7X3) Pfam (PF00380) | Escherichia coli | Small ribosomal subunit protein uS9 |
| 43 | QA (j) | 30S ribosomal protein S10 | polymer | 98 | 11197.0 | 1 | UniProt (P0A7R5) Pfam (PF00338) | Escherichia coli | Small ribosomal subunit protein uS10 |
| 44 | RA (k) | 30S ribosomal protein S11 | polymer | 116 | 12388.1 | 1 | UniProt (P0A7R9) Pfam (PF00411) | Escherichia coli | Small ribosomal subunit protein uS11 |
| 45 | SA (l) | 30S ribosomal protein S12 | polymer | 121 | 13436.7 | 1 | UniProt (P0A7S3) Pfam (PF00164) | Escherichia coli | Small ribosomal subunit protein uS12 |
| 46 | TA (m) | 30S ribosomal protein S13 | polymer | 114 | 12625.8 | 1 | UniProt (P0A7S9) Pfam (PF00416) | Escherichia coli | Small ribosomal subunit protein uS13 |
| 47 | UA (n) | 30S ribosomal protein S14 | polymer | 101 | 11546.4 | 1 | UniProt (P0AG59) Pfam (PF00253) | Escherichia coli | Small ribosomal subunit protein uS14 |
| 48 | VA (o) | 30S ribosomal protein S15 | polymer | 88 | 10159.6 | 1 | UniProt (P0ADZ4) Pfam (PF00312) | Escherichia coli | Small ribosomal subunit protein uS15 |
| 49 | WA (p) | 30S ribosomal protein S16 | polymer | 82 | 9207.6 | 1 | UniProt (P0A7T3) Pfam (PF00886) | Escherichia coli | Small ribosomal subunit protein bS16 |
| 50 | XA (q) | 30S ribosomal protein S17 | polymer | 80 | 9263.9 | 1 | UniProt (P0AG63) Pfam (PF00366) | Escherichia coli | Small ribosomal subunit protein uS17 |
| 51 | YA (r) | 30S ribosomal protein S18 | polymer | 65 | 7606.8 | 1 | UniProt (P0A7T7) Pfam (PF01084) | Escherichia coli | Small ribosomal subunit protein bS18 |
| 52 | ZA (s) | 30S ribosomal protein S19 | polymer | 79 | 9057.6 | 1 | UniProt (P0A7U3) Pfam (PF00203) | Escherichia coli | Small ribosomal subunit protein uS19 |
| 53 | AB (t) | 30S ribosomal protein S20 | polymer | 85 | 9506.2 | 1 | UniProt (P0A7U7) Pfam (PF01649) | Escherichia coli | Small ribosomal subunit protein bS20 |
| 54 | BB (u) | 30S ribosomal protein S21 | polymer | 65 | 7763.1 | 1 | UniProt (P68679) Pfam (PF01165) | Escherichia coli | Small ribosomal subunit protein bS21 |
| 55 | CB, DB (v, w) | tRNA-fMet | polymer | 77 | 24818.9 | 2 | GenBank (731469900) | Escherichia coli | |
| 56 | EB (x) | mRNA | polymer | 12 | 3773.3 | 1 | Escherichia coli | ||
| 57 | FB (y) | Phe-tRNA-Phe | polymer | 76 | 24649.9 | 1 | Escherichia coli | ||
| 58 | GB (z) | Elongation factor Tu 2 | polymer | 393 | 43171.2 | 1 | UniProt (P0CE48) Pfam (PF00009) Pfam (PF03144) Pfam (PF03143) | Escherichia coli | EF-Tu 2,Bacteriophage Q beta RNA-directed RNA polymerase subunit III,P-43 |
| 59 | HB (A) | N-FORMYLMETHIONINE | non-polymer | 177.2 | 1 | Chemie (FME) PubChem (911) PubChem (439750) PubChem (6995182) | |||
| 60 | AAA, ABA, AC, AD, AE... (a, y, A, 3, 4...) | MAGNESIUM ION | non-polymer | 24.3 | 662 | Chemie (MG) PubChem (888) | |||
| 61 | AR, BR, CR, VAA, WQ... (A, v) | POTASSIUM ION | non-polymer | 39.1 | 8 | Chemie (K) PubChem (813) | |||
| 62 | WAA (y) | PHENYLALANINE | non-polymer | 165.2 | 1 | Chemie (PHE) PubChem (994) PubChem (6140) PubChem (71567) | |||
| 63 | BBA (z) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 1 | Chemie (GTP) PubChem (177679032) PubChem (135400627) PubChem (135487750) PubChem (136088935) PubChem (136803486) PubChem (135398633) PubChem (135544356) PubChem (135547949) PubChem (135600366) PubChem (135749822) PubChem (136005188) PubChem (136073923) PubChem (136240914) PubChem (136664747) PubChem (136772743) PubChem (136772744) PubChem (136803487) PubChem (137286749) PubChem (164715984) PubChem (171699466) | |||
| 64 | EBA, FBA, GBA, HBA, IBA... (A, B, C, E, L...) | water | water | 18.0 | 153 | Chemie (HOH) |
Sequence modifications
A: 1 - 2903 (GenBank: 731469900)
B: 1 - 119 (GenBank: 1174070234)
n: 1 - 101 (UniProt: P0AG59)
z: 1 - 393 (UniProt: P0CE48)
| PDB | External Database | Details |
|---|---|---|
| 5mc 747 | U 227841 | conflict |
| G 1723 | A 228817 | conflict |
| G 1847 | A 228941 | conflict |
| PDB | External Database | Details |
|---|---|---|
| A 120 | - | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 35 | - | insertion |
| PDB | External Database | Details |
|---|---|---|
| Asn 47 | Asp 48 | conflict |
| Ala 84 | His 85 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 59 |
| Total formula weight | 2260084.5 | |
| Non-Polymers* | Number of molecules | 673 |
| Total formula weight | 17268.3 | |
| All* | Total formula weight | 2277352.8 |
