5WCT
Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 6c (SRI-29775)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Polymerase acidic protein | polymer | 187 | 21970.2 | 1 | UniProt (C3W5S0) In PDB | Influenza A virus | |
| 2 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 3 | A | 2-{(2S)-1-[(4-chlorophenyl)acetyl]pyrrolidin-2-yl}-5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxylic acid | non-polymer | 377.8 | 1 | Chemie (GY4) | |||
| 4 | water | water | 18.0 | 16 | Chemie (HOH) |
Sequence modifications
A: 1 - 50 (UniProt: C3W5S0)
A: 73 - 196 (UniProt: C3W5S0)
A: 73 - 196 (UniProt: C3W5S0)
| PDB | External Database | Details |
|---|---|---|
| Gly 51 | - | linker |
| Gly 52 | - | linker |
| Ser 53 | - | linker |
| Ala 197 | - | expression tag |
| Ala 198 | - | expression tag |
| Ala 199 | - | expression tag |
| Glu 200 | - | expression tag |
| Leu 201 | - | expression tag |
| Ala 202 | - | expression tag |
| Leu 203 | - | expression tag |
| Val 204 | - | expression tag |
| Pro 205 | - | expression tag |
| Arg 206 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21970.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 487.7 | |
| All* | Total formula weight | 22457.8 |
