5WCI

Human MYST histone acetyltransferase 1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Histone acetyltransferase KAT8	polymer	295	34458.6	1	UniProt (Q9H7Z6) Pfam (PF17772) Pfam (PF01853) In PDB	Homo sapiens (Human)	Lysine acetyltransferase 8,MOZ,YBF2/SAS3,SAS2 and TIP60 protein 1,hMOF
2	A	ZINC ION	non-polymer		65.4	1	Chemie (ZN)
3	A	propionyl Coenzyme A	non-polymer		823.6	1	Chemie (1VU)
4	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
5	A	1,2-ETHANEDIOL	non-polymer		62.1	4	Chemie (EDO)
6		water	water		18.0	237	Chemie (HOH)

Sequence modifications

A: 174 - 449 (UniProt: Q9H7Z6)

PDB	External Database	Details
Met 155	-	initiating methionine
Gly 156	-	expression tag
Ser 157	-	expression tag
Ser 158	-	expression tag
His 159	-	expression tag
His 160	-	expression tag
His 161	-	expression tag
His 162	-	expression tag
His 163	-	expression tag
His 164	-	expression tag
Ser 165	-	expression tag
Ser 166	-	expression tag
Gly 167	-	expression tag
Leu 168	-	expression tag
Val 169	-	expression tag
Pro 170	-	expression tag
Arg 171	-	expression tag
Gly 172	-	expression tag
Ser 173	-	expression tag
His 249	Tyr 249	conflict
Asn 372	Ile 372	conflict

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34458.6
Non-Polymers*	Number of molecules	7
	Total formula weight	1172.7
All*	Total formula weight	35631.4

*Water molecules are not included.