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5WCI

Human MYST histone acetyltransferase 1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Histone acetyltransferase KAT8polymer29534458.61UniProt (Q9H7Z6)
Pfam (PF17772)
Pfam (PF01853)
Homo sapiens (Human)Lysine acetyltransferase 8,MOZ,YBF2/SAS3,SAS2 and TIP60 protein 1,hMOF
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
propionyl Coenzyme Anon-polymer823.61Chemie (1VU)
4D
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
5E, F, G, H
(A)
1,2-ETHANEDIOLnon-polymer62.14Chemie (EDO)
6I
(A)
waterwater18.0237Chemie (HOH)
Sequence modifications
A: 174 - 449 (UniProt: Q9H7Z6)
PDBExternal DatabaseDetails
Met 155-initiating methionine
Gly 156-expression tag
Ser 157-expression tag
Ser 158-expression tag
His 159-expression tag
His 160-expression tag
His 161-expression tag
His 162-expression tag
His 163-expression tag
His 164-expression tag
Ser 165-expression tag
Ser 166-expression tag
Gly 167-expression tag
Leu 168-expression tag
Val 169-expression tag
Pro 170-expression tag
Arg 171-expression tag
Gly 172-expression tag
Ser 173-expression tag
His 249Tyr 249conflict
Asn 372Ile 372conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34458.6
Non-Polymers*Number of molecules7
Total formula weight1172.7
All*Total formula weight35631.4
*Water molecules are not included.

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PDB entries from 2025-07-23

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