5WBH
Structure of the FRB domain of mTOR bound to a substrate recruitment peptide of S6K1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E | Serine/threonine-protein kinase mTOR | polymer | 102 | 12091.7 | 5 | UniProt (P42345) Pfam (PF08771) In PDB | Homo sapiens (Human) | FK506-binding protein 12-rapamycin complex-associated protein 1,FKBP12-rapamycin complex-associated protein,Mammalian target of rapamycin,mTOR,Mechanistic target of rapamycin,Rapamycin and FKBP12 target 1,Rapamycin target protein 1 |
| 2 | W | Ribosomal protein S6 kinase beta-1 | polymer | 26 | 3057.5 | 1 | UniProt (P23443) In PDB | Homo sapiens (Human) | S6K1,70 kDa ribosomal protein S6 kinase 1,p70-S6K 1,Ribosomal protein S6 kinase I,Serine/threonine-protein kinase 14A,p70 ribosomal S6 kinase alpha,p70 S6KA |
| 3 | water | water | 18.0 | 334 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 2018 - 2114 (UniProt: P42345)
| PDB | External Database | Details |
|---|---|---|
| Gly 2016 | - | expression tag |
| Ser 2017 | - | expression tag |
| Ser 2115 | - | expression tag |
| Gly 2116 | - | expression tag |
| Gly 2117 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 63516.3 | |
| All* | Total formula weight | 63516.3 |
