5WB0
Crystal structure of human metapneumovirus fusion glycoprotein stabilized in the prefusion state
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | F | Fusion glycoprotein F0 | polymer | 542 | 59332.3 | 1 | UniProt (Q1A2Z0) Pfam (PF00523) In PDB | Human metapneumovirus | |
2 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
3 | B | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
4 | F | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
5 | F | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
6 | water | water | 18.0 | 135 | Chemie (HOH) |
Sequence modifications
F: 1 - 489 (UniProt: Q1A2Z0)
PDB | External Database | Details |
---|---|---|
Arg 100 | Gln 100 | engineered mutation |
Arg 101 | Ser 101 | engineered mutation |
Pro 185 | Ala 185 | engineered mutation |
Ser 490 | - | expression tag |
Gly 491 | - | expression tag |
Arg 492 | - | expression tag |
Glu 493 | - | expression tag |
Asn 494 | - | expression tag |
Leu 495 | - | expression tag |
Tyr 496 | - | expression tag |
Phe 497 | - | expression tag |
Gln 498 | - | expression tag |
Gly 499 | - | expression tag |
Gly 500 | - | expression tag |
Gly 501 | - | expression tag |
Gly 502 | - | expression tag |
Ser 503 | - | expression tag |
Gly 504 | - | expression tag |
Tyr 505 | - | expression tag |
Ile 506 | - | expression tag |
Pro 507 | - | expression tag |
Glu 508 | - | expression tag |
Ala 509 | - | expression tag |
Pro 510 | - | expression tag |
Arg 511 | - | expression tag |
Asp 512 | - | expression tag |
Gly 513 | - | expression tag |
Gln 514 | - | expression tag |
Ala 515 | - | expression tag |
Tyr 516 | - | expression tag |
Val 517 | - | expression tag |
Arg 518 | - | expression tag |
Lys 519 | - | expression tag |
Asp 520 | - | expression tag |
Gly 521 | - | expression tag |
Glu 522 | - | expression tag |
Trp 523 | - | expression tag |
Val 524 | - | expression tag |
Leu 525 | - | expression tag |
Leu 526 | - | expression tag |
Ser 527 | - | expression tag |
Thr 528 | - | expression tag |
Phe 529 | - | expression tag |
Leu 530 | - | expression tag |
Gly 531 | - | expression tag |
Gly 532 | - | expression tag |
Ile 533 | - | expression tag |
Glu 534 | - | expression tag |
Gly 535 | - | expression tag |
Arg 536 | - | expression tag |
His 537 | - | expression tag |
His 538 | - | expression tag |
His 539 | - | expression tag |
His 540 | - | expression tag |
His 541 | - | expression tag |
His 542 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 59332.3 | |
Branched | Number of molecules | 2 |
Total formula weight | 1173.1 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 605.5 | |
All* | Total formula weight | 61110.8 |