5WB0
Crystal structure of human metapneumovirus fusion glycoprotein stabilized in the prefusion state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (F) | Fusion glycoprotein F0 | polymer | 542 | 59332.3 | 1 | UniProt (Q1A2Z0) Pfam (PF00523) | Human metapneumovirus | |
| 2 | B (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | C (B) | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 1 | In PDB GlyTouCan (G81315DD) | |||
| 4 | D (F) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E, F, G, H (F) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 6 | I (F) | water | water | 18.0 | 135 | Chemie (HOH) |
Sequence modifications
F: 1 - 489 (UniProt: Q1A2Z0)
| PDB | External Database | Details |
|---|---|---|
| Arg 100 | Gln 100 | engineered mutation |
| Arg 101 | Ser 101 | engineered mutation |
| Pro 185 | Ala 185 | engineered mutation |
| Ser 490 | - | expression tag |
| Gly 491 | - | expression tag |
| Arg 492 | - | expression tag |
| Glu 493 | - | expression tag |
| Asn 494 | - | expression tag |
| Leu 495 | - | expression tag |
| Tyr 496 | - | expression tag |
| Phe 497 | - | expression tag |
| Gln 498 | - | expression tag |
| Gly 499 | - | expression tag |
| Gly 500 | - | expression tag |
| Gly 501 | - | expression tag |
| Gly 502 | - | expression tag |
| Ser 503 | - | expression tag |
| Gly 504 | - | expression tag |
| Tyr 505 | - | expression tag |
| Ile 506 | - | expression tag |
| Pro 507 | - | expression tag |
| Glu 508 | - | expression tag |
| Ala 509 | - | expression tag |
| Pro 510 | - | expression tag |
| Arg 511 | - | expression tag |
| Asp 512 | - | expression tag |
| Gly 513 | - | expression tag |
| Gln 514 | - | expression tag |
| Ala 515 | - | expression tag |
| Tyr 516 | - | expression tag |
| Val 517 | - | expression tag |
| Arg 518 | - | expression tag |
| Lys 519 | - | expression tag |
| Asp 520 | - | expression tag |
| Gly 521 | - | expression tag |
| Glu 522 | - | expression tag |
| Trp 523 | - | expression tag |
| Val 524 | - | expression tag |
| Leu 525 | - | expression tag |
| Leu 526 | - | expression tag |
| Ser 527 | - | expression tag |
| Thr 528 | - | expression tag |
| Phe 529 | - | expression tag |
| Leu 530 | - | expression tag |
| Gly 531 | - | expression tag |
| Gly 532 | - | expression tag |
| Ile 533 | - | expression tag |
| Glu 534 | - | expression tag |
| Gly 535 | - | expression tag |
| Arg 536 | - | expression tag |
| His 537 | - | expression tag |
| His 538 | - | expression tag |
| His 539 | - | expression tag |
| His 540 | - | expression tag |
| His 541 | - | expression tag |
| His 542 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 59332.3 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1173.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 605.5 | |
| All* | Total formula weight | 61110.8 |
