5W8H
Crystal Structure of Lactate Dehydrogenase A in complex with inhibitor compound 11
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | L-lactate dehydrogenase A chain | polymer | 332 | 36734.7 | 4 | UniProt (P00338) Pfam (PF00056) Pfam (PF02866) | Homo sapiens (Human) | LDH-A,Cell proliferation-inducing gene 19 protein,LDH muscle subunit,LDH-M,Renal carcinoma antigen NY-REN-59 |
| 2 | E, F, K, N, O... (A, B, C) | 2-[3-(4-fluorophenyl)-5-(trifluoromethyl)-1H-pyrazol-1-yl]-1,3-thiazole-4-carboxylic acid | non-polymer | 357.3 | 7 | Chemie (9Y1) | |||
| 3 | G, H, L, S (A, B, D) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 4 | I, M, T (A, B, D) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 5 | J (B) | MALONIC ACID | non-polymer | 104.1 | 1 | Chemie (MLA) | |||
| 6 | R, U (C, D) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | V, W, X, Y (A, B, C, D) | water | water | 18.0 | 987 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 146938.7 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 3259.8 | |
| All* | Total formula weight | 150198.5 |
