5W81
Phosphorylated, ATP-bound structure of zebrafish cystic fibrosis transmembrane conductance regulator (CFTR)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Cystic fibrosis transmembrane conductance regulator | polymer | 1494 | 169620.8 | 1 | UniProt (Q1LX78) Pfam (PF00664) Pfam (PF00005) Pfam (PF14396) | Danio rerio (Zebrafish) | ATP-binding cassette sub-family C member 7,Channel conductance-controlling ATPase,cAMP-dependent chloride channel |
| 2 | B, C (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 2 | Chemie (ATP) | |||
| 3 | D, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) |
Sequence modifications
A: 1 - 1485 (UniProt: Q1LX78)
| PDB | External Database | Details |
|---|---|---|
| Gln 1372 | Glu 1372 | engineered mutation |
| Ser 1486 | - | expression tag |
| Asn 1487 | - | expression tag |
| Ser 1488 | - | expression tag |
| Leu 1489 | - | expression tag |
| Glu 1490 | - | expression tag |
| Val 1491 | - | expression tag |
| Leu 1492 | - | expression tag |
| Phe 1493 | - | expression tag |
| Gln 1494 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 169620.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1063.0 | |
| All* | Total formula weight | 170683.8 |
