5W7Y
Crystal Structure of FHA domain of human APLF in complex with XRCC1 monophosphorylated mutated peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Aprataxin and PNK-like factor | polymer | 108 | 11921.8 | 2 | UniProt (Q8IW19) Pfam (PF17913) In PDB | Homo sapiens (Human) | Apurinic-apyrimidinic endonuclease APLF,PNK and APTX-like FHA domain-containing protein,XRCC1-interacting protein 1 |
| 2 | D, C | DNA repair protein XRCC1 | polymer | 8 | 960.8 | 2 | UniProt (P18887) In PDB | Homo sapiens | X-ray repair cross-complementing protein 1 |
| 3 | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 105 (UniProt: Q8IW19)
D, C: 514 - 521 (UniProt: P18887)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Phe -1 | - | expression tag |
| Thr 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Glu 518 | Ser 518 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 25765.3 | |
| All* | Total formula weight | 25765.3 |
