5W3R
SH2B1 SH2 Domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SH2B adapter protein 1 | polymer | 114 | 12664.4 | 1 | UniProt (Q9NRF2) Pfam (PF00017) | Homo sapiens (Human) | Pro-rich,PH and SH2 domain-containing signaling mediator,PSM,SH2 domain-containing protein 1B |
| 2 | B (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | C, D, E (A) | PHENOL | non-polymer | 94.1 | 3 | Chemie (IPH) | |||
| 4 | F (A) | water | water | 18.0 | 115 | Chemie (HOH) |
Sequence modifications
A: 519 - 628 (UniProt: Q9NRF2)
| PDB | External Database | Details |
|---|---|---|
| Gly 515 | - | expression tag |
| Ser 516 | - | expression tag |
| His 517 | - | expression tag |
| Met 518 | - | expression tag |
| Ala 583 | Glu 583 | engineered mutation |
| Ala 584 | Glu 584 | engineered mutation |
| His 593 | Trp 593 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 12664.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 377.3 | |
| All* | Total formula weight | 13041.7 |
