5W3I
Crystal structure of the influenza virus PA endonuclease in complex with inhibitor 6e (SRI-29685)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Polymerase acidic protein | polymer | 201 | 23653.9 | 1 | UniProt (C3W5S0) In PDB | Influenza A virus | |
2 | A | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
3 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
4 | A | 5-hydroxy-N-(2-methoxyethyl)-6-oxo-2-[(2S)-1-(phenoxyacetyl)pyrrolidin-2-yl]-1,6-dihydropyrimidine-4-carboxamide | non-polymer | 416.4 | 1 | Chemie (GY5) | |||
5 | water | water | 18.0 | 80 | Chemie (HOH) |
Sequence modifications
A: 1 - 50 (UniProt: C3W5S0)
A: 73 - 196 (UniProt: C3W5S0)
A: 73 - 196 (UniProt: C3W5S0)
PDB | External Database | Details |
---|---|---|
Gly 51 | - | linker |
Gly 52 | - | linker |
Ser 53 | - | linker |
Ala 197 | - | expression tag |
Ala 198 | - | expression tag |
Ala 199 | - | expression tag |
Glu 200 | - | expression tag |
Leu 201 | - | expression tag |
Ala 202 | - | expression tag |
Leu 203 | - | expression tag |
Val 204 | - | expression tag |
Pro 205 | - | expression tag |
Arg 206 | - | expression tag |
Gly 207 | - | expression tag |
Ser 208 | - | expression tag |
Ser 209 | - | expression tag |
Ala 210 | - | expression tag |
His 211 | - | expression tag |
His 212 | - | expression tag |
His 213 | - | expression tag |
His 214 | - | expression tag |
His 215 | - | expression tag |
His 216 | - | expression tag |
His 217 | - | expression tag |
His 218 | - | expression tag |
His 219 | - | expression tag |
His 220 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 23653.9 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 618.4 | |
All* | Total formula weight | 24272.3 |