5W1F
Crystal structure of Ni(II)- and Ca(II)-bound human calprotectin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, G, E) | Protein S100-A8 | polymer | 93 | 10837.5 | 4 | UniProt (P05109) Pfam (PF01023) | Homo sapiens (Human) | Calgranulin-A,Calprotectin L1L subunit,Cystic fibrosis antigen,CFAG,Leukocyte L1 complex light chain,Migration inhibitory factor-related protein 8,p8,S100 calcium-binding protein A8,Urinary stone protein band A |
| 2 | B, D, F, H (B, D, H, F) | Protein S100-A9 | polymer | 114 | 13248.0 | 4 | UniProt (P06702) Pfam (PF01023) | Homo sapiens (Human) | Calgranulin-B,Calprotectin L1H subunit,Leukocyte L1 complex heavy chain,Migration inhibitory factor-related protein 14,p14,S100 calcium-binding protein A9 |
| 3 | I, L, O, T, W... (A, B, C, G, H...) | SODIUM ION | non-polymer | 23.0 | 6 | Chemie (NA) | |||
| 4 | AA, CA, DA, J, M... (E, F, A, B, C...) | CALCIUM ION | non-polymer | 40.1 | 10 | Chemie (CA) | |||
| 5 | BA, K, N, Q, V... (F, B, C, D, H...) | NICKEL (II) ION | non-polymer | 58.7 | 6 | Chemie (NI) | |||
| 6 | EA, FA, GA, HA, IA... (A, B, C, D, G...) | water | water | 18.0 | 148 | Chemie (HOH) |
Sequence modifications
A, C, G, E: 1 - 93 (UniProt: P05109)
B, D, H, F: 1 - 114 (UniProt: P06702)
| PDB | External Database | Details |
|---|---|---|
| Ser 42 | Cys 42 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 3 | Cys 3 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 96341.7 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 890.9 | |
| All* | Total formula weight | 97232.5 |
