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5W0M

Structure of human TUT7 catalytic module (CM) in complex with U5 RNA

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Terminal uridylyltransferase 7polymer38944721.83UniProt (Q5VYS8)
Pfam (PF22600)
Pfam (PF03828)
Pfam (PF00098)
Homo sapiens (Human)TUT7, TUTase 7, Zinc finger CCHC domain-containing protein 6
2D, E, F
(H, I, J)
U5 single-stranded RNApolymer51485.93synthetic construct
3G, H, K, M
(A, B, C)
SULFATE IONnon-polymer96.14Chemie (SO4)
4I, N
(A, C)
ZINC IONnon-polymer65.42Chemie (ZN)
5J, L, O, P
(A, B, C)
IODIDE IONnon-polymer126.94Chemie (IOD)
6Q, R, S, T, U...
(A, B, C, H, I...)
waterwater18.0205Chemie (HOH)
Sequence modifications
A, B, C: 983 - 1365 (UniProt: Q5VYS8)
PDBExternal DatabaseDetails
Gly 977-expression tag
Ala 978-expression tag
Gly 979-expression tag
Ala 980-expression tag
Gly 981-expression tag
Ser 982-expression tag
Ala 1060Asp 1060engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight138623.1
Non-Polymers*Number of molecules10
Total formula weight1022.7
All*Total formula weight139645.7
*Water molecules are not included.

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PDB entries from 2026-01-21

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