5W0M
Structure of human TUT7 catalytic module (CM) in complex with U5 RNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | Terminal uridylyltransferase 7 | polymer | 389 | 44721.8 | 3 | UniProt (Q5VYS8) Pfam (PF22600) Pfam (PF03828) Pfam (PF00098) In PDB | Homo sapiens (Human) | TUT7, TUTase 7, Zinc finger CCHC domain-containing protein 6 |
| 2 | H, I, J | U5 single-stranded RNA | polymer | 5 | 1485.9 | 3 | synthetic construct | ||
| 3 | A, B, C | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 4 | A, C | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 5 | A, B, C | IODIDE ION | non-polymer | 126.9 | 4 | Chemie (IOD) | |||
| 6 | water | water | 18.0 | 205 | Chemie (HOH) |
Sequence modifications
A, B, C: 983 - 1365 (UniProt: Q5VYS8)
| PDB | External Database | Details |
|---|---|---|
| Gly 977 | - | expression tag |
| Ala 978 | - | expression tag |
| Gly 979 | - | expression tag |
| Ala 980 | - | expression tag |
| Gly 981 | - | expression tag |
| Ser 982 | - | expression tag |
| Ala 1060 | Asp 1060 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 138623.1 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1022.7 | |
| All* | Total formula weight | 139645.7 |
