5W0D
Inferred precursor (UCA) of the human antibody lineage K03.12 in complex with influenza hemagglutinin H1 Solomon Islands/03/2006
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Hemagglutinin HA1 | polymer | 223 | 25140.0 | 1 | UniProt (D1MPH2) Pfam (PF00509) UniProt (by SIFTS) (A7UPX0) | Influenza A virus (A/Solomon Islands/3/2006(H1N1)) | |
| 2 | B (B) | Lineage K03.12 UCA antibody heavy chain | polymer | 244 | 26570.8 | 1 | UniProt (S6B2A6) Pfam (PF07686) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C (C) | Lineage K03.12 UCA antibody light chain | polymer | 214 | 22403.7 | 1 | UniProt (Q6IPQ0) Pfam (PF07686) Pfam (PF07654) | Homo sapiens (Human) | |
| 4 | D, E (D, E) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 5 | F (F) | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 1 | In PDB GlyTouCan (G15407YE) | |||
| 6 | G, H (A, B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 7 | I (C) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 8 | J, K, L (A, B, C) | water | water | 18.0 | 246 | Chemie (HOH) |
Sequence modifications
A: 52 - 267 (UniProt: D1MPH2)
B: 1 - 133 (PDB: 5W0D)
B: 134 - 238 (UniProt: S6B2A6)
C: 1 - 113 (PDB: 5W0D)
C: 114 - 214 (UniProt: Q6IPQ0)
| PDB | External Database | Details |
|---|---|---|
| Ala 50 | - | expression tag |
| Ser 51 | - | expression tag |
| Leu 268 | - | expression tag |
| Glu 269 | - | expression tag |
| Val 270 | - | expression tag |
| Leu 271 | - | expression tag |
| Phe 272 | - | expression tag |
B: 134 - 238 (UniProt: S6B2A6)
| PDB | External Database | Details |
|---|---|---|
| His 239 | - | expression tag |
| His 240 | - | expression tag |
| His 241 | - | expression tag |
| His 242 | - | expression tag |
| His 243 | - | expression tag |
| His 244 | - | expression tag |
C: 114 - 214 (UniProt: Q6IPQ0)
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 74114.6 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 1435.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 482.6 | |
| All* | Total formula weight | 76032.5 |
