5W0D

Inferred precursor (UCA) of the human antibody lineage K03.12 in complex with influenza hemagglutinin H1 Solomon Islands/03/2006

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Hemagglutinin HA1	polymer	223	25140.0	1	UniProt (D1MPH2) UniProt (by SIFTS) (A7UPX0)	Influenza A virus (A/Solomon Islands/3/2006(H1N1))
2	B (B)	Lineage K03.12 UCA antibody heavy chain	polymer	244	26570.8	1	UniProt (S6B2A6)	Homo sapiens (Human)
3	C (C)	Lineage K03.12 UCA antibody light chain	polymer	214	22403.7	1	UniProt (Q6IPQ0)	Homo sapiens (Human)
4	D, E (D, E)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	2	In PDB GlyTouCan (G42666HT)
5	F (F)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
6	G, H (A, B)	2-(N-MORPHOLINO)-ETHANESULFONIC ACID	non-polymer		195.2	2	Chemie (MES)
7	I (C)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
8	J, K, L (A, B, C)	water	water		18.0	246	Chemie (HOH)

Sequence modifications

A: 52 - 267 (UniProt: D1MPH2)

PDB	External Database	Details
Ala 50	-	expression tag
Ser 51	-	expression tag
Leu 268	-	expression tag
Glu 269	-	expression tag
Val 270	-	expression tag
Leu 271	-	expression tag
Phe 272	-	expression tag

B: 1 - 133 (PDB: 5W0D)
B: 134 - 238 (UniProt: S6B2A6)

PDB	External Database	Details
His 239	-	expression tag
His 240	-	expression tag
His 241	-	expression tag
His 242	-	expression tag
His 243	-	expression tag
His 244	-	expression tag

C: 1 - 113 (PDB: 5W0D)
C: 114 - 214 (UniProt: Q6IPQ0)

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	74114.6
Branched	Number of molecules	3
	Total formula weight	1435.3
Non-Polymers*	Number of molecules	3
	Total formula weight	482.6
All*	Total formula weight	76032.5

*Water molecules are not included.