5W0C
Cytochrome P450 (CYP) 2C9 TCA007 Inhibitor Complex
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Cytochrome P450 2C9 | polymer | 477 | 54322.9 | 1 | UniProt (P11712) Pfam (PF00067) In PDB | Homo sapiens (Human) | (R)-limonene 6-monooxygenase,(S)-limonene 6-monooxygenase,(S)-limonene 7-monooxygenase,CYPIIC9,Cholesterol 25-hydroxylase,Cytochrome P-450MP,Cytochrome P450 MP-4,Cytochrome P450 MP-8,Cytochrome P450 PB-1,S-mephenytoin 4-hydroxylase |
2 | A | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
3 | A | ethyl {2-[([1,3]thiazolo[4,5-c]pyridine-2-carbonyl)amino]thiophene-3-carbonyl}carbamate | non-polymer | 376.4 | 1 | Chemie (9W6) | |||
4 | A | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
5 | water | water | 18.0 | 211 | Chemie (HOH) |
Sequence modifications
A: 23 - 489 (UniProt: P11712)
PDB | External Database | Details |
---|---|---|
Met 18 | - | initiating methionine |
Ala 19 | - | expression tag |
Lys 20 | - | expression tag |
Lys 21 | - | expression tag |
Thr 22 | - | expression tag |
Ile 490 | - | expression tag |
His 491 | - | expression tag |
His 492 | - | expression tag |
His 493 | - | expression tag |
His 494 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 54322.9 | |
Non-Polymers* | Number of molecules | 3 |
Total formula weight | 1085.0 | |
All* | Total formula weight | 55407.9 |