5VZL
cryo-EM structure of the Cas9-sgRNA-AcrIIA4 anti-CRISPR complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | single guide RNA (116-MER) | polymer | 118 | 38292.6 | 1 | Streptococcus pyogenes M1 GAS | ||
| 2 | B (A) | CRISPR-associated endonuclease Cas9 | polymer | 1369 | 158772.9 | 1 | UniProt (A0A0C6FZC2) Pfam (PF16593) Pfam (PF16592) Pfam (PF13395) Pfam (PF22702) Pfam (PF16595) UniProt (by SIFTS) (Q99ZW2) | Streptococcus pyogenes M1 GAS | |
| 3 | C (C) | phage anti-CRISPR AcrIIA4 | polymer | 87 | 10182.1 | 1 | UniProt (by SIFTS) (A0A2D0TCG7) | unidentified phage |
Sequence modifications
A: 1 - 1368 (UniProt: A0A0C6FZC2)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 207247.6 | |
| All* | Total formula weight | 207247.6 |






