5VZ5
Crystal structure of an anaplastic lymphoma kinase-derived neuroblastoma tumor antigen bound to the Human Major Histocompatibility Complex Class I molecule HLA-B*1501
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class I histocompatibility antigen, B-15 alpha chain | polymer | 280 | 32347.6 | 1 | UniProt (P30464) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P01889) | Homo sapiens (Human) | MHC class I antigen B*15 |
| 2 | B (B) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 1 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (Human) | |
| 3 | C (C) | Tyrosine-protein kinase receptor | polymer | 10 | 1250.3 | 1 | UniProt (B6D4Y8) UniProt (by SIFTS) (Q9UM73) | Homo sapiens | |
| 4 | D, E, F, G, H... (A, B, C) | GLYCEROL | non-polymer | 92.1 | 7 | Chemie (GOL) | |||
| 5 | I, J, K, L, M (A) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 6 | P, Q, R (A, B, C) | water | water | 18.0 | 24 | Chemie (HOH) |
Sequence modifications
B: 1 - 99 (UniProt: P61769)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 45477.3 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1125.0 | |
| All* | Total formula weight | 46602.2 |
