5VYQ
Crystal structure of the N-formyltransferase Rv3404c from mycobacterium tuberculosis in complex with YDP-Qui4N and folinic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Uncharacterized protein | polymer | 255 | 29033.7 | 2 | UniProt (R4MIX2) Pfam (PF00551) Pfam (PF18216) UniProt (by SIFTS) (P9WKZ3) | Mycobacterium tuberculosis CAS/NITR204 | |
| 2 | C (A) | N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid | non-polymer | 473.4 | 1 | Chemie (FON) | |||
| 3 | D (A) | dTDP-4-amino-4,6-dideoxyglucose | non-polymer | 547.3 | 1 | Chemie (0FX) | |||
| 4 | E, F, O, P (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 5 | G, H, L, S (A, B) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 6 | I, K, Q (A, B) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 7 | J, R (A, B) | 3-[4-(2-HYDROXYETHYL)PIPERAZIN-1-YL]PROPANE-1-SULFONIC ACID | non-polymer | 252.3 | 2 | Chemie (EP1) | |||
| 8 | M (A) | LITHIUM ION | non-polymer | 6.9 | 1 | Chemie (LI) | |||
| 9 | N (B) | THYMIDINE-5'-DIPHOSPHATE | non-polymer | 402.2 | 1 | Chemie (TYD) | |||
| 10 | T (B) | POTASSIUM ION | non-polymer | 39.1 | 1 | Chemie (K) | |||
| 11 | U, V (A, B) | water | water | 18.0 | 666 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 235 (UniProt: R4MIX2)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | initiating methionine |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Arg -7 | - | expression tag |
| Asn -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Tyr -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Gly -1 | - | expression tag |
| His 0 | - | expression tag |
| Met 1 | - | expression tag |
| Val 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 58067.5 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2420.3 | |
| All* | Total formula weight | 60487.8 |
