5VX3
Bcl-xL in complex with Bim-h3Pc-RT
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E, G | Bcl-2-like protein 1 | polymer | 158 | 17918.0 | 4 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB | Homo sapiens (Human) | Bcl2-L-1,Apoptosis regulator Bcl-X,Bcl2-L-1,Apoptosis regulator Bcl-X |
2 | B, D, F, H | Bcl-2-like protein 11 | polymer | 26 | 3241.6 | 4 | UniProt (O43521) Pfam (PF08945) In PDB | Homo sapiens | Bcl2-L-11,Bcl2-interacting mediator of cell death |
3 | A, C, E, F, G... | 1,2-ETHANEDIOL | non-polymer | 62.1 | 13 | Chemie (EDO) | |||
4 | water | water | 18.0 | 415 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 1 - 26 (UniProt: Q07817)
A, C, E, G: 83 - 209 (UniProt: Q07817)
B, D, F, H: 83 - 108 (UniProt: O43521)
PDB | External Database | Details |
---|---|---|
Gly -4 | - | expression tag |
Pro -3 | - | expression tag |
Leu -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
B, D, F, H: 83 - 108 (UniProt: O43521)
PDB | External Database | Details |
---|---|---|
Arg 89 | Trp 147 | engineered mutation |
Thr 104 | Tyr 162 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 84638.4 | |
Non-Polymers* | Number of molecules | 13 |
Total formula weight | 806.9 | |
All* | Total formula weight | 85445.3 |