5VX0

Bak in complex with Bim-h3Glg

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Bcl-2 homologous antagonist/killer	polymer	170	19037.3	2	UniProt (Q16611) Pfam (PF00452)	Homo sapiens (Human)	Apoptosis regulator BAK,Bcl-2-like protein 7,Bcl2-L-7
2	B, D (B, D)	Bcl-2-like protein 11	polymer	26	3256.6	2	UniProt (O43521) Pfam (PF08945)	Homo sapiens	Bcl2-L-11,Bcl2-interacting mediator of cell death
3	E, F, G, H, I... (A, C)	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
4	K (C)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
5	L, M, N, O (A, B, C, D)	water	water		18.0	434	Chemie (HOH)

Sequence modifications

A, C: 23 - 186 (UniProt: Q16611)

PDB	External Database	Details
Gly 17	-	expression tag
Pro 18	-	expression tag
Leu 19	-	expression tag
Gly 20	-	expression tag
Ser 21	-	expression tag
Met 22	-	expression tag
Ser 166	Cys 166	engineered mutation

B, D: 141 - 166 (UniProt: O43521)

PDB	External Database	Details
Arg 147	Trp 147	engineered mutation
Thr 162	Tyr 162	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	44587.9
Non-Polymers*	Number of molecules	7
	Total formula weight	207.9
All*	Total formula weight	44795.8

*Water molecules are not included.