5VWZ
Bak in complex with Bim-h3Pc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Bcl-2 homologous antagonist/killer | polymer | 170 | 19037.3 | 2 | UniProt (Q16611) Pfam (PF00452) | Homo sapiens (Human) | Apoptosis regulator BAK,Bcl-2-like protein 7,Bcl2-L-7 |
| 2 | B, D (B, D) | Bcl-2-like protein 11 | polymer | 26 | 3332.7 | 2 | UniProt (O43521) Pfam (PF08945) | Homo sapiens | Bcl2-L-11,Bcl2-interacting mediator of cell death |
| 3 | E, F (C) | 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL | non-polymer | 252.3 | 2 | Chemie (1PG) | |||
| 4 | G (D) | AMMONIUM ION | non-polymer | 18.0 | 1 | Chemie (NH4) | |||
| 5 | H, I, J, K (A, B, C, D) | water | water | 18.0 | 390 | Chemie (HOH) |
Sequence modifications
A, C: 23 - 186 (UniProt: Q16611)
| PDB | External Database | Details |
|---|---|---|
| Gly 17 | - | expression tag |
| Pro 18 | - | expression tag |
| Leu 19 | - | expression tag |
| Gly 20 | - | expression tag |
| Ser 21 | - | expression tag |
| Met 22 | - | expression tag |
| Ser 166 | Cys 166 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 44740.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 522.6 | |
| All* | Total formula weight | 45262.7 |
