5VWY

Bak core latch dimer in complex with Bim-h3Pc-RT

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Bcl-2 homologous antagonist/killer	polymer	170	19037.3	1	UniProt (Q16611) Pfam (PF00452) In PDB	Homo sapiens (Human)	Apoptosis regulator BAK,Bcl-2-like protein 7,Bcl2-L-7
2	B	Bcl-2-like protein 11	polymer	26	3241.6	1	UniProt (O43521) Pfam (PF08945) In PDB	Homo sapiens	Bcl2-L-11,Bcl2-interacting mediator of cell death
3	A	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
4		water	water		18.0	138	Chemie (HOH)

Sequence modifications

A: 23 - 186 (UniProt: Q16611)

PDB	External Database	Details
Gly 17	-	expression tag
Pro 18	-	expression tag
Leu 19	-	expression tag
Gly 20	-	expression tag
Ser 21	-	expression tag
Met 22	-	expression tag
Ser 166	Cys 166	engineered mutation

B: 141 - 166 (UniProt: O43521)

PDB	External Database	Details
Arg 147	Trp 147	engineered mutation
Thr 162	Tyr 162	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	22279.0
Non-Polymers*	Number of molecules	1
	Total formula weight	95.0
All*	Total formula weight	22373.9

*Water molecules are not included.