5VWY
Bak core latch dimer in complex with Bim-h3Pc-RT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Bcl-2 homologous antagonist/killer | polymer | 170 | 19037.3 | 1 | UniProt (Q16611) Pfam (PF00452) | Homo sapiens (Human) | Apoptosis regulator BAK,Bcl-2-like protein 7,Bcl2-L-7 |
| 2 | B (B) | Bcl-2-like protein 11 | polymer | 26 | 3241.6 | 1 | UniProt (O43521) Pfam (PF08945) | Homo sapiens | Bcl2-L-11,Bcl2-interacting mediator of cell death |
| 3 | C (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 4 | D, E (A, B) | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence modifications
A: 23 - 186 (UniProt: Q16611)
B: 141 - 166 (UniProt: O43521)
| PDB | External Database | Details |
|---|---|---|
| Gly 17 | - | expression tag |
| Pro 18 | - | expression tag |
| Leu 19 | - | expression tag |
| Gly 20 | - | expression tag |
| Ser 21 | - | expression tag |
| Met 22 | - | expression tag |
| Ser 166 | Cys 166 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Arg 147 | Trp 147 | engineered mutation |
| Thr 162 | Tyr 162 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 22279.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 95.0 | |
| All* | Total formula weight | 22373.9 |
