5VVO
Structural Investigations of the Substrate Specificity of Human O-GlcNAcase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protein O-GlcNAcase | polymer | 504 | 57822.6 | 2 | UniProt (O60502) Pfam (PF07555) | Homo sapiens (Human) | OGA,Beta-N-acetylglucosaminidase,Beta-N-acetylhexosaminidase,Beta-hexosaminidase,Meningioma-expressed antigen 5,N-acetyl-beta-D-glucosaminidase,N-acetyl-beta-glucosaminidase,Nuclear cytoplasmic O-GlcNAcase and acetyltransferase,NCOAT |
| 2 | C, D (A, B) | water | water | 18.0 | 132 | Chemie (HOH) |
Sequence modifications
A, B: 60 - 400 (UniProt: O60502)
A, B: 553 - 704 (UniProt: O60502)
| PDB | External Database | Details |
|---|---|---|
| His 59 | - | expression tag |
| Asn 175 | Asp 175 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gly 543 | - | linker |
| Gly 544 | - | linker |
| Gly 545 | - | linker |
| Gly 546 | - | linker |
| Ser 547 | - | linker |
| Gly 548 | - | linker |
| Gly 549 | - | linker |
| Gly 550 | - | linker |
| Gly 551 | - | linker |
| Ser 552 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 115645.2 | |
| All* | Total formula weight | 115645.2 |
