5VTZ

Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin G225Q/L226A mutant apo form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, C, E)	Hemagglutinin HA1 chain	polymer	323	35535.9	3	UniProt (Q91MA7) Pfam (PF00509)	Influenza A virus (strain A/Hong Kong/1/1968 H3N2)
2	B, D, F (B, D, F)	Hemagglutinin HA2 chain	polymer	174	20041.1	3	UniProt (Q91MA7) Pfam (PF00509)	Influenza A virus (strain A/Hong Kong/1/1968 H3N2)
3	G, H, J (G, H, J)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	3	In PDB GlyTouCan (G15407YE)
4	I, K, M (I, K, M)	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	3	In PDB GlyTouCan (G42666HT)
5	L (L)	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		910.8	1	In PDB GlyTouCan (G22768VO)
6	N, O, P, Q (A, C, E)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	4	Chemie (NAG)
7	R, S, T, U, V... (A, B, C, D, E...)	water	water		18.0	875	Chemie (HOH)

Sequence modifications

A, C, E: 11 - 329 (UniProt: Q91MA7)

PDB	External Database	Details
Ala 7	-	expression tag
Asp 8	-	expression tag
Pro 9	-	expression tag
Gly 10	-	expression tag
Gln 225	Gly 241	engineered mutation
Ala 226	Leu 242	engineered mutation

B, D, F: 1 - 174 (UniProt: Q91MA7)

PDB	External Database	Details
Gly 123	Arg 468	conflict

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	166731.2
Branched	Number of molecules	7
	Total formula weight	3943.7
Non-Polymers*	Number of molecules	4
	Total formula weight	884.8
All*	Total formula weight	171559.7

*Water molecules are not included.