5VT6

Crystal structure of Acetoacetyl-CoA Reductase from Burkholderia pseudomallei 1710b complexed with NADP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Acetoacetyl-CoA reductase	polymer	269	28779.8	4	UniProt (Q3JJT1) Pfam (PF13561)	Burkholderia pseudomallei (strain 1710b)
2	E, L, P, V (A, B, C, D)	NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE	non-polymer		743.4	4	Chemie (NAP)
3	F, M, Q, W, X (A, B, C, D)	ACETATE ION	non-polymer		59.0	5	Chemie (ACT)
4	G, H, I, J, K... (A, B, C, D)	1,2-ETHANEDIOL	non-polymer		62.1	11	Chemie (EDO)
5	O, U (B, C)	IMIDAZOLE	non-polymer		69.1	2	Chemie (IMD)
6	AA, BA, CA, DA (A, B, C, D)	water	water		18.0	1008	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 248 (UniProt: Q3JJT1)

PDB	External Database	Details
Met -20	-	expression tag
Ala -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Met -12	-	expression tag
Gly -11	-	expression tag
Thr -10	-	expression tag
Leu -9	-	expression tag
Glu -8	-	expression tag
Ala -7	-	expression tag
Gln -6	-	expression tag
Thr -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Pro -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	115119.4
Non-Polymers*	Number of molecules	22
	Total formula weight	4089.8
All*	Total formula weight	119209.1

*Water molecules are not included.