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5VSW

X-ray crystal structure of Escherichia coli RNA polymerase and DksA/ppGpp complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, G, H
(A, B, G, H)
DNA-directed RNA polymerase subunit alphapolymer32936558.74UniProt (P0A7Z4)
Pfam (PF01193)
Pfam (PF01000)
Pfam (PF03118)
Escherichia coli (strain K12)RNAP subunit alpha,RNA polymerase subunit alpha,Transcriptase subunit alpha
2C, I
(C, I)
DNA-directed RNA polymerase subunit betapolymer1342150820.92UniProt (P0A8V2)
Pfam (PF04560)
Pfam (PF04563)
Pfam (PF04561)
Pfam (PF04565)
Pfam (PF10385)
Pfam (PF00562)
Escherichia coli (strain K12)RNAP subunit beta,RNA polymerase subunit beta,Transcriptase subunit beta
3D, J
(D, J)
DNA-directed RNA polymerase subunit beta'polymer1407155366.82UniProt (P0A8T7)
Pfam (PF04997)
Pfam (PF00623)
Pfam (PF04983)
Pfam (PF05000)
Pfam (PF04998)
Escherichia coli (strain K12)RNAP subunit beta',RNA polymerase subunit beta',Transcriptase subunit beta'
4E, K
(E, K)
DNA-directed RNA polymerase subunit omegapolymer9110249.52UniProt (P0A800)
Pfam (PF01192)
Escherichia coli (strain K12)RNAP omega subunit,RNA polymerase omega subunit,Transcriptase subunit omega
5F, L
(F, L)
RNA polymerase sigma factor RpoDpolymer61370352.22UniProt (P00579)
Pfam (PF03979)
Pfam (PF00140)
Pfam (PF04546)
Pfam (PF04542)
Pfam (PF04539)
Pfam (PF04545)
Escherichia coli (strain K12)Sigma-70
6M
(M)
RNA polymerase-binding transcription factor DksApolymer15117554.81UniProt (P0ABS1)
Pfam (PF21157)
Pfam (PF01258)
Escherichia coli (strain K12)DnaK suppressor protein
7N, R
(D, J)
MAGNESIUM IONnon-polymer24.32Chemie (MG)
8O, P, S, T, V
(D, J, M)
ZINC IONnon-polymer65.45Chemie (ZN)
9Q, U, W
(E, J, M)
GUANOSINE-5',3'-TETRAPHOSPHATEnon-polymer603.23Chemie (G4P)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains13
Total formula weight937368.4
Non-Polymers*Number of molecules10
Total formula weight2185.1
All*Total formula weight939553.5
*Water molecules are not included.

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PDB entries from 2026-01-14

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