5VSF
Structure of human GLP SET-domain (EHMT1) in complex with inhibitor 17
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Histone-lysine N-methyltransferase EHMT1 | polymer | 261 | 30232.4 | 2 | UniProt (Q9H9B1) Pfam (PF05033) Pfam (PF00856) | Homo sapiens (Human) | Euchromatic histone-lysine N-methyltransferase 1,Eu-HMTase1,G9a-like protein 1,GLP1,Histone H3-K9 methyltransferase 5,H3-K9-HMTase 5,Lysine N-methyltransferase 1D |
| 2 | C, K (A, B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) PubChem (5136) PubChem (34755) PubChem (58633578) PubChem (60038769) PubChem (58766358) PubChem (73897310) PubChem (9865603) PubChem (87224684) PubChem (12312798) PubChem (131697735) PubChem (145712080) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) | |||
| 3 | D, E, F, G, L... (A, B) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 4 | H, P (A, B) | N~2~-cyclopentyl-6,7-dimethoxy-N~2~-methyl-N~4~-(1-methylpiperidin-4-yl)quinazoline-2,4-diamine | non-polymer | 399.5 | 2 | Chemie (9HG) PubChem (129012137) | |||
| 5 | I (A) | 1,4-DIETHYLENE DIOXIDE | non-polymer | 88.1 | 1 | Chemie (DIO) | |||
| 6 | J, Q (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 7 | R, S (A, B) | water | water | 18.0 | 492 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60464.7 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2391.5 | |
| All* | Total formula weight | 62856.2 |
