5VS4

Human DNA polymerase beta 8-oxoG:dA extension with dTTP after 120 s

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	T	DNA (5'-D(*CP*CP*GP*AP*CP*AP*(8OG)P*GP*CP*GP*CP*AP*TP*CP*AP*G)-3')	polymer	16	4909.2	1		synthetic construct
2	P	DNA (5'-D(*CP*TP*GP*AP*TP*GP*CP*GP*CP*AP*T)-3')	polymer	11	3349.2	1		synthetic construct
3	D	DNA (5'-D(P*GP*TP*CP*GP*G)-3')	polymer	5	1536.0	1		synthetic construct
4	A	DNA polymerase beta	polymer	341	39070.5	1	UniProt (P06746) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) In PDB	Homo sapiens (Human)
5	P, D, A	MAGNESIUM ION	non-polymer		24.3	6	Chemie (MG)
6	P	PYROPHOSPHATE	non-polymer		178.0	1	Chemie (PPV)
7	A	ACETATE ION	non-polymer		59.0	3	Chemie (ACT)
8		water	water		18.0	340	Chemie (HOH)

Sequence modifications

A: 1 - 335 (UniProt: P06746)

PDB	External Database	Details
His 336	-	expression tag
His 337	-	expression tag
His 338	-	expression tag
His 339	-	expression tag
His 340	-	expression tag
His 341	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	48865.0
Non-Polymers*	Number of molecules	10
	Total formula weight	500.9
All*	Total formula weight	49365.9

*Water molecules are not included.