5VPM

Crystal Structure of Human Renin in Complex with a biphenylpipderidinylcarbinol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Renin	polymer	337	36939.6	2	UniProt (P00797) Pfam (PF00026)	Homo sapiens (Human)	Angiotensinogenase
2	C, F (A, B)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
3	D, G (A, B)	methyl [(4S)-4-(3'-ethyl-6-fluoro[1,1'-biphenyl]-2-yl)-4-hydroxy-4-{(3R)-1-[(piperidin-4-yl)acetyl]piperidin-3-yl}butyl]carbamate	non-polymer		553.7	2	Chemie (9G7)
4	E, H (A, B)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
5	I, J (A, B)	water	water		18.0	10	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	73879.2
Non-Polymers*	Number of molecules	6
	Total formula weight	1742.0
All*	Total formula weight	75621.1

*Water molecules are not included.