5VOY

Yeast V-ATPase in complex with Legionella pneumophila effector SidK (rotational state 2)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E (A, C, E)	V-type proton ATPase catalytic subunit A,V-type proton ATPase catalytic subunit A	polymer	617	67796.5	3	UniProt (P17255) Pfam (PF02874) Pfam (PF16886) Pfam (PF00006) Pfam (PF22919)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	V-ATPase subunit A,Vacuolar proton pump subunit A,V-ATPase subunit A,Vacuolar proton pump subunit A
2	B, D, F (B, D, F)	V-type proton ATPase subunit B	polymer	517	57815.0	3	UniProt (P16140) Pfam (PF02874) Pfam (PF00006) Pfam (PF22919)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	V-ATPase subunit B,V-ATPase 57 kDa subunit,Vacuolar proton pump subunit B
3	G, I, K (G, I, K)	V-type proton ATPase subunit E	polymer	233	26508.4	3	UniProt (P22203) Pfam (PF01991)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	V-ATPase subunit E,V-ATPase 27 kDa subunit,Vacuolar proton pump subunit E
4	H, J, L (H, J, L)	V-type proton ATPase subunit G	polymer	114	12738.7	3	UniProt (P48836) Pfam (PF03179)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	V-ATPase subunit G,V-ATPase 13 kDa subunit,Vacuolar proton pump subunit G
5	M (M)	V-type proton ATPase subunit D	polymer	256	29235.0	1	UniProt (P32610) Pfam (PF01813)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	V-ATPase subunit D,Vacuolar proton pump subunit D
6	N (N)	V-type proton ATPase subunit F	polymer	118	13479.2	1	UniProt (P39111) Pfam (PF01990)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	V-ATPase subunit F,V-ATPase 14 kDa subunit,Vacuolar proton pump subunit F
7	O (O)	V-type proton ATPase subunit C	polymer	392	44241.4	1	UniProt (P31412) Pfam (PF03223)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	V-ATPase subunit C,V-ATPase 42 kDa subunit,Vacuolar proton pump subunit C
8	P (P)	V-type proton ATPase subunit H	polymer	478	54482.6	1	UniProt (P41807) Pfam (PF03224) Pfam (PF11698)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	V-ATPase subunit H,V-ATPase 54 kDa subunit,Vacuolar proton pump subunit H
9	Q (Q)	V-type proton ATPase subunit d	polymer	345	39822.5	1	UniProt (P32366) Pfam (PF01992)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	V-ATPase subunit d,V-ATPase 39 kDa subunit,V-ATPase subunit M39,Vacuolar proton pump subunit d
10	R (R)	V-type proton ATPase subunit c''	polymer	213	22610.6	1	UniProt (P23968) Pfam (PF00137)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	V-ATPase subunit c'',V-ATPase 22 kDa proteolipid subunit,Vacuolar proton pump c'' subunit
11	S (S)	V-type proton ATPase subunit c'	polymer	164	17046.4	1	UniProt (P32842) Pfam (PF00137)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	V-ATPase subunit c',Proteolipid protein VMA11,Trifluoperazine resistance protein 3,V-ATPase 16 kDa proteolipid subunit 2,Vacuolar proton pump c' subunit
12	AA, T, U, V, W... (T, U, V, W, X...)	V-type proton ATPase subunit c	polymer	160	16357.5	8	UniProt (P25515) Pfam (PF00137)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	V-ATPase subunit c,Guanine nucleotide exchange factor 2,V-ATPase 16 kDa proteolipid subunit 1,Vacuolar proton pump c subunit
13	BA (b)	V-type proton ATPase subunit a, vacuolar isoform	polymer	840	95625.5	1	UniProt (P32563) Pfam (PF01496)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	V-ATPase a 1 subunit,V-ATPase 95 kDa subunit,Vacuolar pH protein 1,Vacuolar proton pump a subunit,Vacuolar proton translocating ATPase subunit a 1
14	CA (c)	V-type proton ATPase subunit e	polymer	73	8387.1	1	UniProt (Q3E7B6) Pfam (PF05493)	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)	V-ATPase subunit e,Low dye-binding protein 10,Vacuolar proton pump subunit e
15	DA (d)	V-type proton ATPase subunit f	polymer	54	4613.7	1		Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
16	EA, FA, GA (e, f, g)	effector protein SidK	polymer	573	65490.3	3	UniProt (G8UUS6)	Legionella pneumophila subsp. pneumophila ATCC 43290

Sequence modifications

A, C, E: 1 - 283 (UniProt: P17255)
A, C, E: 738 - 1071 (UniProt: P17255)
e, f, g: 1 - 573 (UniProt: G8UUS6)

PDB	External Database	Details
Leu 89	Gln 89	conflict

Contents of the asymmetric unit

Polymers	Number of chains	33
	Total formula weight	1151450.7
All*	Total formula weight	1151450.7

*Water molecules are not included.