5VOF
DesGla-XaS195A Bound to Aptamer 11F7t and Rivaroxaban
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Coagulation factor X | polymer | 233 | 26330.0 | 1 | UniProt (P00742) Pfam (PF00089) | Homo sapiens (Human) | Stuart factor,Stuart-Prower factor |
| 2 | B (L) | Coagulation factor X | polymer | 51 | 5460.1 | 1 | UniProt (P00742) Pfam (PF14670) | Homo sapiens (Human) | Stuart factor,Stuart-Prower factor |
| 3 | C (A) | DNA/RNA (36-MER) | polymer | 36 | 11538.7 | 1 | synthetic construct | ||
| 4 | D (H) | 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide | non-polymer | 435.9 | 1 | Chemie (RIV) | |||
| 5 | E (H) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | F (H) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 7 | G, H (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 8 | I, J, K (H, L, A) | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
H: 16 - 243 (UniProt: P00742)
| PDB | External Database | Details |
|---|---|---|
| Ala 195 | Ser 419 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 43328.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 547.6 | |
| All* | Total formula weight | 43876.3 |
