5VN8
Cryo-EM model of B41 SOSIP.664 in complex with fragment antigen binding variable domain of b12
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | G, D, E | Envelope glycoprotein gp160 | polymer | 516 | 57702.5 | 3 | UniProt (B3UES2) Pfam (PF00516) In PDB | Human immunodeficiency virus 1 | |
2 | A, B, C | Envelope glycoprotein gp160 | polymer | 153 | 17357.8 | 3 | UniProt (B3UEZ6) Pfam (PF00517) In PDB | Human immunodeficiency virus 1 | |
3 | H, F, I | b12 Fab heavy chain | polymer | 230 | 24910.8 | 3 | Homo sapiens | ||
4 | L, J, K | b12 Fab light chain | polymer | 215 | 23707.4 | 3 | Homo sapiens (Human) | ||
5 | b, c, d, g, h... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 21 | In PDB GlyTouCan (G42666HT) | |||
6 | e, f, k, O, p... | beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 586.5 | 9 | In PDB GlyTouCan (G15407YE) | |||
7 | a, l, P | alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 3 | In PDB GlyTouCan (G81315DD) | |||
8 | A, D, B, E, G... | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 33 | Chemie (NAG) |
Sequence modifications
G, D, E: 31 - 505 (UniProt: B3UES2)
A, B, C: 512 - 664 (UniProt: B3UEZ6)
PDB | External Database | Details |
---|---|---|
Met -4 | - | initiating methionine |
Asp -3 | - | expression tag |
Ala -2 | - | expression tag |
Met -1 | - | expression tag |
Lys 0 | - | expression tag |
Arg 1 | - | expression tag |
Gly 2 | - | expression tag |
Leu 3 | - | expression tag |
Cys 4 | - | expression tag |
Cys 5 | - | expression tag |
Val 6 | - | expression tag |
Leu 7 | - | expression tag |
Leu 8 | - | expression tag |
Leu 9 | - | expression tag |
Cys 10 | - | expression tag |
Gly 11 | - | expression tag |
Ala 12 | - | expression tag |
Val 13 | - | expression tag |
Phe 14 | - | expression tag |
Val 15 | - | expression tag |
Ser 16 | - | expression tag |
Pro 17 | - | expression tag |
Ser 18 | - | expression tag |
Gln 19 | - | expression tag |
Glu 20 | - | expression tag |
Ile 21 | - | expression tag |
His 22 | - | expression tag |
Ala 23 | - | expression tag |
Arg 24 | - | expression tag |
Phe 25 | - | expression tag |
Arg 26 | - | expression tag |
Arg 27 | - | expression tag |
Gly 28 | - | expression tag |
Ala 29 | - | expression tag |
Arg 30 | - | expression tag |
Cys 501 | Ala 505 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Pro 559 | Ile 563 | engineered mutation |
Cys 605 | Thr 609 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 12 |
Total formula weight | 371035.5 | |
Branched | Number of molecules | 33 |
Total formula weight | 16437.3 | |
Non-Polymers* | Number of molecules | 33 |
Total formula weight | 7299.9 | |
All* | Total formula weight | 394772.7 |