5VN4

Crystal structure of adenine phosphoribosyl transferase from Trypanosoma brucei in complex with AMP, pyrophosphate, and ribose-5-phosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Adenine phosphoribosyltransferase, putative	polymer	243	27035.2	2	UniProt (Q57V32) Pfam (PF00156) In PDB	Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
2	A, B	ADENINE	non-polymer		135.1	2	Chemie (ADE)
3	A, B	5-O-phosphono-alpha-D-ribofuranose	non-polymer		230.1	2	Chemie (HSX)
4	A, B	PYROPHOSPHATE	non-polymer		178.0	2	Chemie (PPV)
5	A	MAGNESIUM ION	non-polymer		24.3	1	Chemie (MG)
6		water	water		18.0	643	Chemie (HOH)

Sequence modifications

A, B: 1 - 235 (UniProt: Q57V32)

PDB	External Database	Details
Met -7	-	initiating methionine
Ala -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	54070.4
Non-Polymers*	Number of molecules	7
	Total formula weight	1110.7
All*	Total formula weight	55181.1

*Water molecules are not included.