5VJM
Crystal structure of H7 hemagglutinin mutant (V186K, K193T, G228S) from the influenza virus A/Shanghai/2/2013 (H7N9) with LSTa
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Hemagglutinin HA1 | polymer | 325 | 35365.9 | 1 | UniProt (R4NN21) Pfam (PF00509) In PDB | Influenza A virus | |
2 | B | Hemagglutinin HA2 | polymer | 183 | 21081.2 | 1 | UniProt (R4NN21) Pfam (PF00509) In PDB | Influenza A virus | |
3 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
4 | A | N-acetyl-alpha-neuraminic acid | non-polymer | 309.3 | 1 | Chemie (SIA) | |||
5 | A | METHANOL | non-polymer | 32.0 | 1 | Chemie (MOH) | |||
6 | water | water | 18.0 | 10 | Chemie (HOH) |
Sequence modifications
A: 11 - 330 (UniProt: R4NN21)
B: 1 - 176 (UniProt: R4NN21)
PDB | External Database | Details |
---|---|---|
Ala 7 | - | expression tag |
Asp 8 | - | expression tag |
Pro 9 | - | expression tag |
Gly 10 | - | expression tag |
Lys 186 | Val 195 | engineered mutation |
Thr 193 | Lys 202 | engineered mutation |
Ser 228 | Gly 237 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Ser 177 | - | expression tag |
Gly 178 | - | expression tag |
Arg 179 | - | expression tag |
Leu 180 | - | expression tag |
Val 181 | - | expression tag |
Pro 182 | - | expression tag |
Arg 183 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 56447.1 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 1004.9 | |
All* | Total formula weight | 57452.0 |