5VJK

Crystal structure of H7 hemagglutinin mutant (V186K, K193T, G228S) from the influenza virus A/Shanghai/2/2013 (H7N9)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Hemagglutinin HA1	polymer	325	35365.9	1	UniProt (R4NN21)	Influenza A virus
2	B (B)	Hemagglutinin HA2	polymer	183	21081.2	1	UniProt (R4NN21)	Influenza A virus
3	C (C)	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
4	D, E (A)	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	2	Chemie (NAG)
5	F, G (A, B)	water	water		18.0	71	Chemie (HOH)

Sequence modifications

A: 11 - 330 (UniProt: R4NN21)

PDB	External Database	Details
Ala 7	-	expression tag
Asp 8	-	expression tag
Pro 9	-	expression tag
Gly 10	-	expression tag
Lys 186	Val 195	engineered mutation
Thr 193	Lys 202	engineered mutation
Ser 228	Gly 237	engineered mutation

B: 1 - 176 (UniProt: R4NN21)

PDB	External Database	Details
Ser 177	-	expression tag
Gly 178	-	expression tag
Arg 179	-	expression tag
Leu 180	-	expression tag
Val 181	-	expression tag
Pro 182	-	expression tag
Arg 183	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	56447.1
Branched	Number of molecules	1
	Total formula weight	586.5
Non-Polymers*	Number of molecules	2
	Total formula weight	442.4
All*	Total formula weight	57476.1

*Water molecules are not included.