5VIN

Crystal Structure of the R515Q missense variant of human PGM1

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Phosphoglucomutase-1	polymer	585	64162.7	2	UniProt (P36871) Pfam (PF02878) Pfam (PF02879) Pfam (PF02880) In PDB	Homo sapiens (Human)	PGM 1,Glucose phosphomutase 1
2	A, B	SULFATE ION	non-polymer		96.1	13	Chemie (SO4)
3	A, B	GLYCEROL	non-polymer		92.1	6	Chemie (GOL)
4	A, B	COBALT (II) ION	non-polymer		58.9	2	Chemie (CO)
5		water	water		18.0	91	Chemie (HOH)

Sequence modifications

A, B: 1 - 562 (UniProt: P36871)

PDB	External Database	Details
Met -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Ser -15	-	expression tag
Ser -14	-	expression tag
Gly -13	-	expression tag
Val -12	-	expression tag
Asp -11	-	expression tag
Leu -10	-	expression tag
Gly -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Ser -1	-	expression tag
Asn 0	-	expression tag
Gln 515	Arg 515	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	128325.3
Non-Polymers*	Number of molecules	21
	Total formula weight	1919.2
All*	Total formula weight	130244.6

*Water molecules are not included.