5VIL
Crystal structure of ASK1 kinase domain with a potent inhibitor (analog 6)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Mitogen-activated protein kinase kinase kinase 5 | polymer | 293 | 32979.6 | 4 | UniProt (Q99683) Pfam (PF00069) In PDB | Homo sapiens (Human) | Apoptosis signal-regulating kinase 1,ASK-1,MAPK/ERK kinase kinase 5,MEKK 5 |
| 2 | A, B, C, D | 2-methoxy-N-{6-[4-(propan-2-yl)-4H-1,2,4-triazol-3-yl]pyridin-2-yl}-5-sulfamoylbenzamide | non-polymer | 416.5 | 4 | Chemie (9E1) | |||
| 3 | A, B | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 4 | Chemie (DMS) | |||
| 4 | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 131918.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 1978.3 | |
| All* | Total formula weight | 133896.8 |
