5VHH
Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | 26S proteasome regulatory subunit 7 | polymer | 352 | 39395.4 | 1 | UniProt (P35998) Pfam (PF21236) Pfam (PF00004) Pfam (PF17862) In PDB | Homo sapiens (Human) | 26S proteasome AAA-ATPase subunit RPT1,Proteasome 26S subunit ATPase 2,Protein MSS1 |
2 | B | 26S proteasome regulatory subunit 4 | polymer | 340 | 37968.3 | 1 | UniProt (P62191) Pfam (PF16450) Pfam (PF00004) Pfam (PF17862) In PDB | Homo sapiens (Human) | P26s4,26S proteasome AAA-ATPase subunit RPT2,Proteasome 26S subunit ATPase 1 |
3 | C | 26S proteasome regulatory subunit 8 | polymer | 385 | 43201.1 | 1 | UniProt (P62195) Pfam (PF16450) Pfam (PF00004) Pfam (PF17862) In PDB | Homo sapiens (Human) | 26S proteasome AAA-ATPase subunit RPT6,Proteasome 26S subunit ATPase 5,Proteasome subunit p45,Thyroid hormone receptor-interacting protein 1,TRIP1,p45/SUG |
4 | D | 26S proteasome regulatory subunit 6B | polymer | 368 | 41723.8 | 1 | UniProt (P43686) Pfam (PF16450) Pfam (PF00004) Pfam (PF17862) In PDB | Homo sapiens (Human) | 26S proteasome AAA-ATPase subunit RPT3,MB67-interacting protein,MIP224,Proteasome 26S subunit ATPase 4,Tat-binding protein 7,TBP-7 |
5 | E | 26S proteasome regulatory subunit 10B | polymer | 379 | 43112.7 | 1 | UniProt (P62333) Pfam (PF16450) Pfam (PF00004) Pfam (PF17862) In PDB | Homo sapiens (Human) | 26S proteasome AAA-ATPase subunit RPT4,Proteasome 26S subunit ATPase 6,Proteasome subunit p42 |
6 | F | 26S proteasome regulatory subunit 6A | polymer | 380 | 42467.9 | 1 | UniProt (P17980) Pfam (PF16450) Pfam (PF00004) Pfam (PF17862) In PDB | Homo sapiens (Human) | 26S proteasome AAA-ATPase subunit RPT5,Proteasome 26S subunit ATPase 3,Proteasome subunit P50,Tat-binding protein 1,TBP-1 |
7 | U | 26S proteasome non-ATPase regulatory subunit 1 | polymer | 935 | 103755.0 | 1 | UniProt (Q99460) Pfam (PF21505) Pfam (PF01851) Pfam (PF13646) Pfam (PF18004) In PDB | Homo sapiens (Human) | 26S proteasome regulatory subunit RPN2,26S proteasome regulatory subunit S1,26S proteasome subunit p112 |
8 | V | 26S proteasome non-ATPase regulatory subunit 3 | polymer | 488 | 55703.7 | 1 | UniProt (O43242) Pfam (PF01399) Pfam (PF08375) In PDB | Homo sapiens (Human) | 26S proteasome regulatory subunit RPN3,26S proteasome regulatory subunit S3,Proteasome subunit p58 |
9 | W | 26S proteasome non-ATPase regulatory subunit 12 | polymer | 456 | 52979.4 | 1 | UniProt (O00232) Pfam (PF22241) Pfam (PF01399) Pfam (PF18098) In PDB | Homo sapiens (Human) | 26S proteasome regulatory subunit RPN5,26S proteasome regulatory subunit p55 |
10 | X | 26S proteasome non-ATPase regulatory subunit 11 | polymer | 385 | 43427.1 | 1 | UniProt (O00231) Pfam (PF18055) Pfam (PF01399) Pfam (PF18503) In PDB | Homo sapiens (Human) | 26S proteasome regulatory subunit RPN6,26S proteasome regulatory subunit S9,26S proteasome regulatory subunit p44.5 |
11 | Y | 26S proteasome non-ATPase regulatory subunit 6 | polymer | 378 | 44336.9 | 1 | UniProt (Q15008) Pfam (PF10602) Pfam (PF01399) Pfam (PF21154) In PDB | Homo sapiens (Human) | 26S proteasome regulatory subunit RPN7,26S proteasome regulatory subunit S10,Breast cancer-associated protein SGA-113M,Phosphonoformate immuno-associated protein 4,Proteasome regulatory particle subunit p44S10,p42A |
12 | Z | 26S proteasome non-ATPase regulatory subunit 7 | polymer | 286 | 32382.1 | 1 | UniProt (P51665) Pfam (PF01398) Pfam (PF13012) In PDB | Homo sapiens (Human) | 26S proteasome regulatory subunit RPN8,26S proteasome regulatory subunit S12,Mov34 protein homolog,Proteasome subunit p40 |
13 | a | 26S proteasome non-ATPase regulatory subunit 13 | polymer | 374 | 42735.0 | 1 | UniProt (Q9UNM6) Pfam (PF22037) Pfam (PF01399) In PDB | Homo sapiens (Human) | 26S proteasome regulatory subunit RPN9,26S proteasome regulatory subunit S11,26S proteasome regulatory subunit p40.5 |
14 | b | 26S proteasome non-ATPase regulatory subunit 4 | polymer | 191 | 20866.0 | 1 | UniProt (P55036) Pfam (PF13519) In PDB | Homo sapiens (Human) | 26S proteasome regulatory subunit RPN10,26S proteasome regulatory subunit S5A,Antisecretory factor 1,ASF,Multiubiquitin chain-binding protein |
15 | c | 26S proteasome non-ATPase regulatory subunit 14 | polymer | 287 | 32329.4 | 1 | UniProt (O00487) Pfam (PF01398) In PDB | Homo sapiens (Human) | 26S proteasome regulatory subunit RPN11,26S proteasome-associated PAD1 homolog 1 |
16 | d | 26S proteasome non-ATPase regulatory subunit 8 | polymer | 257 | 30039.7 | 1 | UniProt (P48556) Pfam (PF10075) In PDB | Homo sapiens (Human) | 26S proteasome regulatory subunit RPN12,26S proteasome regulatory subunit S14,p31 |
17 | e | 26S proteasome complex subunit SEM1 | polymer | 70 | 8284.6 | 1 | UniProt (P60896) Pfam (PF05160) In PDB | Homo sapiens (Human) | 26S proteasome complex subunit DSS1,Deleted in split hand/split foot protein 1,Split hand/foot deleted protein 1,Split hand/foot malformation type 1 protein |
18 | G | 26S proteasome non-ATPase regulatory subunit 10 | polymer | 223 | 24142.5 | 1 | UniProt (O75832) Pfam (PF12796) In PDB | Homo sapiens (Human) | 26S proteasome regulatory subunit p28,Gankyrin,p28(GANK) |
19 | f | 26S proteasome non-ATPase regulatory subunit 2 | polymer | 848 | 93790.2 | 1 | UniProt (Q13200) Pfam (PF17781) Pfam (PF01851) In PDB | Homo sapiens (Human) | 26S proteasome regulatory subunit RPN1,26S proteasome regulatory subunit S2,26S proteasome subunit p97,Protein 55.11,Tumor necrosis factor type 1 receptor-associated protein 2 |
20 | c | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 19 |
Total formula weight | 832640.8 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 65.4 | |
All* | Total formula weight | 832706.2 |