5VH3

Crystal structure of Fab fragment of the anti-TNFa antibody infliximab in a C-centered orthorhombic crystal form

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (H, A)	Infliximab Fab Heavy Chain	polymer	226	24356.2	2		Mus musculus
2	B, D (L, B)	Infliximab Fab Light Chain	polymer	214	23460.9	2		Mus musculus
3	E (B)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
4	F, G, H, I (H, L, A, B)	water	water		18.0	1046	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	95634.1
Non-Polymers*	Number of molecules	1
	Total formula weight	62.1
All*	Total formula weight	95696.2

*Water molecules are not included.