5VH2

Crystal Structure of Mouse Cadherin-23 EC12-13 with Engineered Mutation S1339D

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Cadherin-23	polymer	220	24263.9	4	UniProt (Q99PF4) Pfam (PF00028)	Mus musculus (Mouse)	Otocadherin
2	E, F, G, I, J... (A, B, C, D)	CALCIUM ION	non-polymer		40.1	10	Chemie (CA)
3	H, L, O, R (A, B, C, D)	SODIUM ION	non-polymer		23.0	4	Chemie (NA)

Sequence modifications

A, B, C, D: 1179 - 1389 (UniProt: Q99PF4)

PDB	External Database	Details
Met 1178	-	initiating methionine
Asp 1316	Ser 1339	engineered mutation
Leu 1390	-	expression tag
Glu 1391	-	expression tag
His 1392	-	expression tag
His 1393	-	expression tag
His 1394	-	expression tag
His 1395	-	expression tag
His 1396	-	expression tag
His 1397	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	97055.8
Non-Polymers*	Number of molecules	14
	Total formula weight	492.7
All*	Total formula weight	97548.5

*Water molecules are not included.