5VEE
PAK4 kinase domain in complex with FRAX486
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Serine/threonine-protein kinase PAK 4 | polymer | 319 | 36025.7 | 1 | UniProt (O96013) Pfam (PF00069) In PDB | Homo sapiens (Human) | p21-activated kinase 4,PAK-4 |
| 2 | A | 6-(2,4-dichlorophenyl)-8-ethyl-2-{[3-fluoro-4-(piperazin-1-yl)phenyl]amino}pyrido[2,3-d]pyrimidin-7(8H)-one | non-polymer | 513.4 | 1 | Chemie (981) |
Sequence modifications
A: 286 - 591 (UniProt: O96013)
| PDB | External Database | Details |
|---|---|---|
| Gly 273 | - | expression tag |
| Ala 274 | - | expression tag |
| Arg 275 | - | expression tag |
| Ala 276 | - | expression tag |
| Arg 277 | - | expression tag |
| Gln 278 | - | expression tag |
| Glu 279 | - | expression tag |
| Asn 280 | - | expression tag |
| Gly 281 | - | expression tag |
| Met 282 | - | expression tag |
| Pro 283 | - | expression tag |
| Glu 284 | - | expression tag |
| Lys 285 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36025.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 513.4 | |
| All* | Total formula weight | 36539.1 |
