Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

5VDU

Human cyclic GMP-AMP synthase (cGAS) in complex with Compound F2

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BCyclic GMP-AMP synthasepolymer36342536.12UniProt (Q8N884)
Pfam (PF03281)
Pfam (PF20266)
In PDB
Homo sapiens (Human)h-cGAS,2'3'-cGAMP synthase,Mab-21 domain-containing protein 1
2A, BZINC IONnon-polymer65.42Chemie (ZN)
3A, B2-(pyridin-2-yl)pyrimidinenon-polymer157.24Chemie (9BS)
4waterwater18.052Chemie (HOH)
Sequence modifications
A, B: 161 - 522 (UniProt: Q8N884)
PDBExternal DatabaseDetails
Met 160-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight85072.2
Non-Polymers*Number of molecules6
Total formula weight759.5
All*Total formula weight85831.7
*Water molecules are not included.

221716

PDB entries from 2024-06-26

PDB statisticsPDBj update infoContact PDBjnumon