5VDQ
Human cyclic GMP-AMP synthase (cGAS) in complex with 2',5'-GpAp
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cyclic GMP-AMP synthase | polymer | 363 | 42536.1 | 2 | UniProt (Q8N884) Pfam (PF03281) Pfam (PF20266) | Homo sapiens (Human) | h-cGAS,2'3'-cGAMP synthase,Mab-21 domain-containing protein 1 |
| 2 | C, E (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, F (A, B) | 2',5'-GpAp | non-polymer | 692.4 | 2 | Chemie (9BG) |
Sequence modifications
A, B: 161 - 522 (UniProt: Q8N884)
| PDB | External Database | Details |
|---|---|---|
| Met 160 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 85072.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1515.7 | |
| All* | Total formula weight | 86587.9 |
