5VC1
Crystal structure of L-selectin lectin/EGF domains
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | L-selectin | polymer | 157 | 18412.7 | 1 | UniProt (P14151) Pfam (PF00059) Pfam (PF00008) | Homo sapiens (Human) | CD62 antigen-like family member L,Leukocyte adhesion molecule 1,LAM-1,Leukocyte surface antigen Leu-8,Leukocyte-endothelial cell adhesion molecule 1,LECAM1,Lymph node homing receptor,TQ1,gp90-MEL |
| 2 | B (B) | beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 910.8 | 1 | In PDB GlyTouCan (G23553FE) | |||
| 3 | C (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 4 | D (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 5 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 6 | F (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 7 | G (A) | water | water | 18.0 | 77 | Chemie (HOH) |
Sequence modifications
A: 1 - 157 (UniProt: P14151)
| PDB | External Database | Details |
|---|---|---|
| Gln 22 | Asn 60 | engineered mutation |
| Gln 139 | Asn 177 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 18412.7 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 910.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 432.5 | |
| All* | Total formula weight | 19756.0 |
