5VB9
IL-17A in complex with peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Interleukin-17A | polymer | 119 | 13750.5 | 2 | UniProt (Q16552) Pfam (PF06083) | Homo sapiens (Human) | IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8 |
| 2 | C, D (C, D) | Peptide inhibitor | polymer | 15 | 1845.2 | 2 | synthetic construct | ||
| 3 | E, F, H (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 4 | G (B) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 280 | Chemie (HOH) |
Sequence modifications
A, B: 15 - 132 (UniProt: Q16552)
| PDB | External Database | Details |
|---|---|---|
| Gly 14 | - | expression tag |
| Asp 45 | Asn 68 | conflict |
| Ser 106 | Cys 129 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 31191.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 221.7 | |
| All* | Total formula weight | 31413.0 |
